Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | ACP1 | P24666 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19189688 | 0.83 | ALDH1A1 (0.40) | TDP1PDE10ATSHRALDH1A1HPGD | |
| SCHEMBL12991538 | 0.79 | TDP1 (0.55) | TDP1PDE10ATSHRALDH1A1HPGD | |
| SCHEMBL13949449 | 0.78 | ALOX15 (0.42) | ALOX15TSHRCREBBPACP1L3MBTL1 | |
| SCHEMBL13335986 | 0.78 | SMN1; SMN2 (0.45) | ALOX15TSHRCREBBPACP1L3MBTL1 | |
| SCHEMBL5910341 | 0.76 | TDP1 (0.47) | TDP1PDE10AALDH1A1HPGDGLA | |
| SCHEMBL3197275 | 0.76 | ACP1 (0.43) | PDE10AALOX15TSHRCREBBPACP1 | |
| SCHEMBL13641185 | 0.75 | PDE10A (0.51) | TDP1PDE10AALDH1A1HPGDGLA | |
| SCHEMBL28029896 | 0.74 | L3MBTL1 (0.43) | TDP1ALOX15TSHRCREBBPACP1 | |
| SCHEMBL7068280 | 0.72 | TDP1 (0.55) | TDP1PDE10AALDH1A1HPGDGLA | |
| SCHEMBL23459716 | 0.71 | KDM4E (0.41) | ALOX15ACP1ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008025509-A1 | BENZOFURAN AND BENZOTHIOPHENE DERIVATIVES USEFUL IN THE TREATMENT OF CANCERS OF THE CENTRAL NERVOUS SYSTEM | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-06 | — | — | WO | disclosed |