Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 3/20 | 0.71 |
| ▸ | TUBB | P07437 | 3/20 | 0.71 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.71 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.71 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.71 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.71 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.71 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.71 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.71 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.71 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.71 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.71 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.71 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.71 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.71 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.66 |
| ▸ | XDH | P47989 | 2/20 | 0.65 |
| ▸ | DPP4 | P27487 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14259664 | 0.91 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14697045 | 0.90 | TUBB4A (0.65) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29358799 | 0.90 | MAPT (0.77) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14259665 | 0.90 | MAPT (0.77) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4101098 | 0.87 | ABCB1 (0.84) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10067898 | 0.87 | ADORA3 (0.71) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL12590664 | 0.86 | MAPT (0.84) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16237902 | 0.86 | KDM4E (0.83) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10037939 | 0.84 | MEN1 (0.76) | CYP1A1CYP1A2CYP1B1XDHDPP4 | |
| SCHEMBL25235022 | 0.84 | ABCB1 (0.79) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080076738-A1 | Phosphonate Analogs Of Hiv Integrase Inhibitor Compounds | GILEAD SCIENCES, INC. | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076738-A1 | Phosphonate Analogs Of Hiv Integrase Inhibitor Compounds | TYMP, PNP, PIKFYVE | TUBB4A 1861/4885TUBB 1287/4885TUBA3C 2323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.