SCHEMBL1425992

SCHEMBL1425992

O=Cc1cc2c(cc1[N+](=O)[O-])OCO2

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.59
MEN1 O00255 5/20 0.59
KMT2A Q03164 5/20 0.59
POLB P06746 4/20 0.59
L3MBTL1 Q9Y468 2/20 0.59
MCL1 Q07820 1/20 0.59
ALDH1A1 P00352 10/20 0.58
KDM4E B2RXH2 6/20 0.58
GAA P10253 4/20 0.58
CYP3A4 P08684 2/20 0.58
CYP1A2 P05177 1/20 0.58
CYP2D6 P10635 1/20 0.58
CYP2C9 P11712 1/20 0.58
CYP2C19 P33261 1/20 0.58
APAF1 O14727 1/20 0.55
HK1 P19367 1/20 0.55
DNMT1 P26358 1/20 0.55
CASP3 P42574 1/20 0.55
SENP8 Q96LD8 1/20 0.55
SENP7 Q9BQF6 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30460431 1.00 MAPT (0.59) MAPTMEN1KMT2APOLBL3MBTL1
SCHEMBL15189023 0.89 MAPT (0.59) MAPTMEN1KMT2APOLBL3MBTL1
SCHEMBL126109 0.84 MAPT (0.57) MAPTMEN1KMT2APOLBL3MBTL1
SCHEMBL718255 0.82 MAPT (0.74) MAPTMEN1KMT2APOLBL3MBTL1
SCHEMBL31692976 0.82 MAPT (0.44) MAPTMEN1KMT2APOLBL3MBTL1
SCHEMBL20739004 0.81 MAPT (0.55) MAPTMEN1KMT2APOLBL3MBTL1
SCHEMBL20722838 0.81 MAPT (0.62) MAPTMEN1KMT2APOLBL3MBTL1
SCHEMBL20723034 0.81 MAPT (0.62) MAPTMEN1KMT2APOLBL3MBTL1
Ammonia Solution, Strong SCHEMBL11877252 0.79 MAPT (0.52) MAPTMEN1KMT2APOLBL3MBTL1
SCHEMBL14070022 0.78 LMNA (0.64) MAPTMEN1KMT2AL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 745 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118931906-A 10-23DNAzyme capable of controlling light-operated bioorthogonal regulation and preparation method and application thereof 兰州交通大学 2024-11-12 CN claimed
CN-118852032-A Alpha, beta-unsaturated ketone derivative, preparation method and application thereof 赣南医科大学 2024-10-29 CN claimed
CN-112920113-A Beta amyloid-targeted fluorescent probe, preparation method thereof and application thereof in Alzheimer's disease 华南理工大学 2021-06-08 CN claimed
CN-110003031-B Amphiphilic molecule containing o-nitrobenzyl ester photodegradation group and synthetic method thereof 大连理工大学 2020-06-02 CN claimed
CN-110003031-A Amphiphilic molecule containing o-nitrobenzyl ester photodegradation group and synthetic method thereof 大连理工大学 2019-07-12 CN claimed
EP-2358343-B1 METHOD FOR DECOLOURING KERATINOUS FIBRES HENKEL AG & CO KGAA (DE) 2016-10-19 EP claimed
US-8268015-B2 Method for decolorizing keratin-containing fibers HENKEL AG & CO. KGAA (DE) 2012-09-18 US claimed
EP-1778176-B1 COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES HENKEL AG & CO KGAA (DE) 2012-07-25 EP claimed
US-20110247644-A1 Method for Decolorizing Keratin-Containing Fibers HENKEL AG & CO. KGAA (DE) 2011-10-13 US claimed
EP-2358343-A2 METHOD FOR DECOLOURING KERATINOUS FIBRES Henkel AG & Co. KGaA (DE) 2011-08-24 EP claimed
EP-1300132-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
EP-1300133-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
WO-2000038634-A1 AGENT FOR DYING KERATIN FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2000-07-06 WO claimed
US-5663029-A DEVELOPMENT OF LATENT IMAGE, TRANSFERRING TO FORM RECORDING SHEETS, COATING A SUBSTRATE USING POLYMERS XEROX CORPORATION (US) 1997-09-02 US claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110247644-A1 Method for Decolorizing Keratin-Containing Fibers KRT18, PLOD3, DSG1 MAPT 125/4885MEN1 4660/4885KMT2A 228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.