Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.58 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.51 |
| ▸ | CTSA | P10619 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14262002 | 0.87 | GAA (0.67) | GAAUTS2RTAS1R3TAS1R1SMN1; SMN2 | |
| SCHEMBL14261991 | 0.87 | GAA (0.62) | GAAUTS2RTAS1R3TAS1R1NPC1 | |
| SCHEMBL14477805 | 0.84 | GAA (1.00) | GAAUTS2RTAS1R3TAS1R1NPC1 | |
| SCHEMBL3141349 | 0.77 | ITGB3 (0.58) | GAARAB9AITGB3ITGA2B | |
| SCHEMBL14261990 | 0.77 | RAB9A (0.59) | GAAUTS2RTAS1R3TAS1R1RAB9A | |
| SCHEMBL29157147 | 0.77 | LMNA (0.58) | GAAUTS2RCYP26A1SMN1; SMN2CTSA | |
| Propionic Acid SCHEMBL11143657 | 0.75 | TAS1R3 (0.65) | GAATAS1R3TAS1R1NPC1RAB9A | |
| SCHEMBL15239028 | 0.75 | KMT2A (0.59) | GAARAB9AITGB3ITGA2B | |
| SCHEMBL15238897 | 0.75 | KMT2A (0.59) | GAARAB9AITGB3ITGA2B | |
| SCHEMBL20976479 | 0.75 | KMT2A (0.59) | GAARAB9AITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348357-B2 | bactericide; derivatives of pseudopeptide Andrimid in which beta-phenylalanine amide is replaced by heteroaromatic or substituted aromatic amide; N-{(1S)-3-[((1S)-1-{[(3R,4S)-1,4-Dimethyl-2,5-dioxo-3-pyrrolidinyl]carbonyl}-2-methylpropyl)amino]-3-oxo-1-phenylpropyl}-2-pyridinecarboxamide; antibiotics | BAYER HEALTHCARE AG (DE) | 2008-03-25 | — | — | US | disclosed |
| US-7348357-B2 | bactericide; derivatives of pseudopeptide Andrimid in which beta-phenylalanine amide is replaced by heteroaromatic or substituted aromatic amide; N-{(1S)-3-[((1S)-1-{[(3R,4S)-1,4-Dimethyl-2,5-dioxo-3-pyrrolidinyl]carbonyl}-2-methylpropyl)amino]-3-oxo-1-phenylpropyl}-2-pyridinecarboxamide; antibiotics | BAYER HEALTHCARE AG (DE) | 2008-03-25 | — | — | US | disclosed |