SCHEMBL14263522

SCHEMBL14263522

Cc1ccc(N=C2C=CC(=NC3(C)C=C(C(C)(C)C)C(=O)C(C(C)(C)C)=C3)C=C2)cc1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.33
▸ GPR55 Q9Y2T6 1/20 0.33
▸ HPGD P15428 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14263569 0.88 POLB (0.43) POLBGPR55SMN1; SMN2
SCHEMBL14263577 0.80 ALOX5 (0.34) POLBHPGD
SCHEMBL14263567 0.75 POLB (0.37) POLBGPR55SMN1; SMN2
SCHEMBL14263523 0.75 POLB (0.37) POLBGPR55SMN1; SMN2
SCHEMBL14253699 0.72 SMN1; SMN2 (0.35) SMN1; SMN2
SCHEMBL14263547 0.71 POLB (0.36) POLBGPR55SMN1; SMN2
SCHEMBL4403176 0.70 ACHE (0.44) POLBHPGDSMN1; SMN2
SCHEMBL16675402 0.67 SMN1; SMN2 (0.57) POLBGPR55HPGDSMN1; SMN2
SCHEMBL14263548 0.67 MEN1 (0.32) SMN1; SMN2
SCHEMBL14315021 0.64 POLB (0.37) POLBGPR55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7341811-B2 Electrophotographic photoreceptor using the electron transferring compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-03-11 — — US disclosed
Send feedback