Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.37 |
| ▸ | MEN1 | O00255 | 7/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14264013 | 0.90 | TPMT (0.44) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL16769478 | 0.75 | CA5A (0.48) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14275457 | 0.75 | TPMT (0.67) | NPC1KMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL14264012 | 0.73 | TPMT (0.61) | RAB9ANPC1SMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL23817375 | 0.70 | TPMT (0.71) | SMN1; SMN2KMT2AMEN1MAPK1TPMT | |
| SCHEMBL18629882 | 0.70 | CA5A (0.48) | KMT2AMEN1TPMTMAPTLMNA | |
| SCHEMBL14264003 | 0.68 | TPMT (0.38) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14277282 | 0.67 | CA5A (0.48) | RAB9ANPC1SMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL96185 | 0.67 | CA5A (0.52) | RAB9ANPC1SMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL15262165 | 0.66 | HDAC8 (0.43) | SMN1; SMN2LMNAALDH1A1HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064848-A1 | Radiopaque amide polymers and medical devices formed thereof | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2008-03-13 | — | — | US | disclosed |