SCHEMBL18629882

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13624841	0.91	CA5A (0.56)	CA5ALMNATTRESR1CYP2C19
	SCHEMBL1644952	0.86	CA5A (0.56)	CA5ALMNAESR1HSD17B1MEN1
	SCHEMBL22991530	0.80	TTR (0.44)	LMNATTRESR1CYP2C19EYA3
	SCHEMBL13144722	0.80	CA5A (0.50)	CA5ALMNAESR1HSD17B1MEN1
	SCHEMBL16769478	0.79	CA5A (0.48)	CA5ALMNAHSD17B1MEN1KMT2A
	SCHEMBL14277282	0.79	CA5A (0.48)	CA5ALMNAESR1HSD17B1KMT2A
	SCHEMBL6900728	0.78	CA5A (0.48)	CA5ALMNAESR1HSD17B1MEN1
	SCHEMBL21854475	0.78	KDM4E (0.57)	LMNAESR1MEN1KMT2ACA1
	SCHEMBL6944075	0.78	LMNA (0.78)	CA5ALMNACYP2C19MEN1KMT2A
	SCHEMBL2716447	0.77	TTR (0.48)	CA5ALMNATTRESR1HSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.