Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15908134 | 0.97 | NPC1 (0.52) | NPC1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL39669 | 0.93 | NPC1 (0.62) | NPC1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL29353657 | 0.93 | NPC1 (0.62) | NPC1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL17920176 | 0.93 | NPC1 (0.62) | NPC1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL195208 | 0.90 | NPC1 (0.59) | NPC1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL15910010 | 0.90 | NPC1 (0.59) | NPC1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL807727 | 0.90 | NPC1 (0.59) | NPC1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL19756253 | 0.90 | NPC1 (0.66) | NPC1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL17571546 | 0.89 | TSHR (0.59) | NPC1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL12216381 | 0.88 | NPC1 (0.53) | NPC1KMT2AMEN1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7344706-B2 | Benzotriazoles, dibenzoylmethane derivatives and camphor derivatives: Ultraviolet filters in cosmetic compositions | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-03-18 | — | — | US | disclosed |