SCHEMBL39669

SCHEMBL39669

COc1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)c(O)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.62
SMN1; SMN2 Q16637 4/20 0.56
MAPT P10636 4/20 0.56
RAB9A P51151 4/20 0.56
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
NFKB1 P19838 2/20 0.56
NFKB2 Q00653 2/20 0.56
RELA Q04206 2/20 0.56
PTPN1 P18031 1/20 0.56
NCOA1 Q15788 1/20 0.55
NCOA3 Q9Y6Q9 1/20 0.55
ALDH1A1 P00352 2/20 0.52
HTT P42858 2/20 0.52
KDM4E B2RXH2 2/20 0.52
TP53 P04637 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
HSD17B10 Q99714 1/20 0.52
ADORA3 P0DMS8 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29353657 1.00 NPC1 (0.62) NPC1SMN1; SMN2MAPTRAB9AMEN1
SCHEMBL17920176 1.00 NPC1 (0.62) NPC1SMN1; SMN2MAPTRAB9AMEN1
SCHEMBL195208 0.97 NPC1 (0.59) NPC1SMN1; SMN2MAPTRAB9AMEN1
SCHEMBL15910010 0.97 NPC1 (0.59) NPC1SMN1; SMN2MAPTRAB9AMEN1
SCHEMBL807727 0.97 NPC1 (0.59) NPC1SMN1; SMN2MAPTRAB9AMEN1
SCHEMBL17571546 0.95 TSHR (0.59) NPC1SMN1; SMN2MAPTRAB9AMEN1
SCHEMBL14264451 0.93 NPC1 (0.55) NPC1SMN1; SMN2MAPTRAB9AMEN1
SCHEMBL13938599 0.92 NPC1 (0.61) NPC1SMN1; SMN2MAPTRAB9AMEN1
SCHEMBL12997352 0.92 NPC1 (0.54) NPC1SMN1; SMN2MAPTRAB9AMEN1
SCHEMBL12228367 0.92 NPC1 (0.54) NPC1SMN1; SMN2MAPTRAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3937 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240084104-A1 ADDITIVE MIXTURES BASF SE (DE) 2024-03-14 US claimed
WO-2023227472-A1 POLYCARBONATE COMPOSITION CONTAINING COMBINATION OF HYDROXYPHENYL TRIAZINES AND UV ABSORBERS BASF SE (DE) 2023-11-30 WO claimed
CN-116547346-A Additive mixture 巴斯夫欧洲公司 2023-08-04 CN claimed
EP-3122819-B1 MELT POLYMERIZATION POLYCARBONATE QUENCHING TECHNICAL FIELD SABIC GLOBAL TECHNOLOGIES BV (NL) 2023-07-19 EP claimed
CN-116367815-A Uv absorbing nanoparticles and microparticles for intradermal use 科罗拉多大学董事会法人团体 2023-06-30 CN claimed
CN-115677837-A Polyglutamic acid sunscreen peptide and preparation method thereof 陕西慧康生物科技有限责任公司 2023-02-03 CN claimed
US-10011095-B2 Synthetic resin laminate MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2018-07-03 US claimed
US-9803049-B2 Melt polymerization polycarbonate quenching SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-10-31 US claimed
EP-3122819-A1 MELT POLYMERIZATION POLYCARBONATE QUENCHING SABIC Global Technologies B.V. (NL) 2017-02-01 EP claimed
US-9543521-B2 Organic semiconductor device and process for its production BASF SE (DE) 2017-01-10 US claimed
US-20030088098-A1 Novel red-shifted triazine ultravioletlight absorbers CYTEC TECHNOLOGY CORP. 2003-05-08 US claimed
WO-2003035733-A1 PROCESS FOR IMPROVING THE SHELF LIFE OF A HINDERED PHENOL ANTIOXIDANT CYTEC TECHNOLOGY CORP. (US) 2003-05-01 WO claimed
US-20030073771-A1 Process for improving the shelf life of a hindered phenol antioxidant CYTEC TECHNOLOGY CORP. 2003-04-17 US claimed
EP-1298126-A1 Novel red-shifted triazine ultraviolet light absorbers CYTEC TECHNOLOGY CORP. (US) 2003-04-02 EP claimed
US-20020161075-A1 Polymeric articles containing hindered amine light stabilizers based on multi-functional carbonyl compounds CYTEC TECHNOLOGY CORP. 2002-10-31 US claimed
WO-2002062885-A2 POLYMERIC ARTICLES CONTAINING HINDERED AMINE LIGHT STABILIZERS BASED ON MULTI-FUNCTIONAL CARBONYL COMPOUNDS CYTEC TECHNOLOGY CORP. (US) 2002-08-15 WO claimed
WO-2002046136-A2 BIS(ALKYLENEOXYBENZOPHENONE) ULTRAVIOLET LIGHT ABSORBERS CYTEC TECHNOLOGY CORP. (US) 2002-06-13 WO claimed
WO-2002036579-A1 NON-YELLOWING ORTHO-DIALKYL ARYL SUBSTITUTED TRIAZINE ULTRAVIOLET LIGHT ABSORBERS CYTEC TECHNOLOGY CORP. (US) 2002-05-10 WO claimed
US-6384113-B1 POLYMER STABILIZER; LOW VOLATILITY; WEATHERABILITY; YELLOWING RESISTANCE CYTEC TECHNOLOGY CORP. 2002-05-07 US claimed
US-20020028937-A1 Benzocycle-substituted triazine and pyrimidine ultraviolet light absorbers CYTEC TECHNOLOGY CORP. 2002-03-07 US claimed