Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | BACE1 | P56817 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.52 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.52 |
| ▸ | IDH1 | O75874 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807727 | 0.97 | NPC1 (0.59) | NPC1BACE1MAPTKMT2AMEN1 | |
| SCHEMBL15910010 | 0.97 | NPC1 (0.59) | NPC1BACE1MAPTKMT2AMEN1 | |
| SCHEMBL29353657 | 0.97 | NPC1 (0.62) | NPC1BACE1MAPTKMT2AMEN1 | |
| SCHEMBL17920176 | 0.97 | NPC1 (0.62) | NPC1BACE1MAPTKMT2AMEN1 | |
| SCHEMBL39669 | 0.97 | NPC1 (0.62) | NPC1BACE1MAPTKMT2AMEN1 | |
| SCHEMBL13658285 | 0.94 | NPC1 (0.66) | NPC1BACE1MAPTKMT2AMEN1 | |
| SCHEMBL6516972 | 0.94 | NPC1 (0.66) | NPC1BACE1MAPTKMT2AMEN1 | |
| SCHEMBL17571546 | 0.93 | TSHR (0.59) | NPC1BACE1MAPTKMT2AMEN1 | |
| SCHEMBL12997145 | 0.92 | NPC1 (0.54) | NPC1BACE1MAPTKMT2AMEN1 | |
| SCHEMBL12997352 | 0.92 | NPC1 (0.54) | NPC1BACE1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0654469-B1 | Stabilised polymers containing o-hydroxyphenyl-s-triazines | CIBA SC HOLDING AG (CH) | 2001-08-22 | — | — | EP | claimed |
| US-20170189277-A1 | COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF | L'OREAL (FR) | 2017-07-06 | — | — | US | disclosed |
| US-20170189277-A1 | COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF | L'OREAL (FR) | 2017-07-06 | — | — | US | disclosed |
| US-9669243-B2 | Delivery of hydrophobic benefit agents from bodywashes and the like onto a keratinous substrate | BASF SE (DE) | 2017-06-06 | — | — | US | disclosed |
| US-9669243-B2 | Delivery of hydrophobic benefit agents from bodywashes and the like onto a keratinous substrate | BASF SE (DE) | 2017-06-06 | — | — | US | disclosed |
| US-20150190320-A1 | COSMETIC COMPOSITION COMPRISING COMPOSITE SUNSCREEN PARTICLES | L'OREAL (FR) | 2015-07-09 | — | — | US | disclosed |
| US-20150190320-A1 | COSMETIC COMPOSITION COMPRISING COMPOSITE SUNSCREEN PARTICLES | L'OREAL (FR) | 2015-07-09 | — | — | US | disclosed |
| US-20150157539-A1 | COSMETIC COMPOSITION COMPRISING COMPOSITE PARTICLES | L'OREAL (FR) | 2015-06-11 | — | — | US | disclosed |
| US-20150157539-A1 | COSMETIC COMPOSITION COMPRISING COMPOSITE PARTICLES | L'OREAL (FR) | 2015-06-11 | — | — | US | disclosed |
| US-8882902-B2 | Composite pigment and method for preparation thereof | L'OREAL (FR) | 2014-11-11 | — | — | US | disclosed |
| EP-0834304-B1 | Use of liposomogenic UV absorbers to protect hair | CIBA SC HOLDING AG (CH) | 2005-01-26 | — | — | EP | disclosed |
| EP-0654469-B1 | Stabilised polymers containing o-hydroxyphenyl-s-triazines | CIBA SC HOLDING AG (CH) | 2001-08-22 | — | — | EP | disclosed |
| EP-0815071-B1 | LIPOSOMOGENIC UV ABSORBERS | CIBA SC HOLDING AG (CH) | 2001-04-11 | — | — | EP | disclosed |
| US-6017556-A | PROTECTING HUMAN HAIR FROM THE DAMAGING EFFECT OF ULTRAVIOLET RADIATION BY TREATING HUMAN HAIR WITH A LIPOSOMOGENIC ULTRAVIOLET RADIATION ABSORBER | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-01-25 | — | — | US | disclosed |
| US-6015575-A | TRIAZINE, BENZOTRIAZOLE, BENZOPHENONE AND AMINOBENZOIC ACID DERIVATIVES AS RADIATION ABSORBERS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-01-18 | — | — | US | disclosed |
| EP-0834304-A2 | Liposomogenic UV absorbers | Ciba SC Holding AG (CH) | 1998-04-08 | — | — | EP | disclosed |
| US-5688995-A | SUNSCREEN AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-11-18 | — | — | US | disclosed |
| US-5591850-A | STABILIZERS FOR TEXTILE FIBERS, COSMETIC SUNSCREENS | CIBA-GEIGY CORPORATION (US) | 1997-01-07 | — | — | US | disclosed |
| EP-0743309-A1 | o-Hydroxyphenyl-s-triazines as UV stabilisers | CIBA-GEIGY AG (CH) | 1996-11-20 | — | — | EP | disclosed |
| EP-0654469-A1 | O-Hydroxyphenyl-s-triazines as stabilisers for polymers | CIBA-GEIGY AG (CH) | 1995-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170189277-A1 | COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF | TYR, RAB5IF, MITF | NPC1 1772/4885BACE1 3380/4885MAPT 1171/4885 |
| US-20150157539-A1 | COSMETIC COMPOSITION COMPRISING COMPOSITE PARTICLES | MITF, RAB5IF, TYR | NPC1 1863/4885BACE1 2970/4885MAPT 922/4885 |
| US-20150190320-A1 | COSMETIC COMPOSITION COMPRISING COMPOSITE SUNSCREEN PARTICLES | XPA, ERCC1, ERCC4 | NPC1 283/4885BACE1 1790/4885MAPT 2352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.