Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1426471 | 1.00 | NPC1 (0.43) | NPC1RAB9AHPGDERCC5FEN1 | |
| SCHEMBL5998808 | 1.00 | NPC1 (0.43) | NPC1RAB9AHPGDERCC5FEN1 | |
| SCHEMBL9723735 | 0.86 | NPC1 (0.45) | NPC1RAB9AHPGDERCC5FEN1 | |
| SCHEMBL5998811 | 0.86 | NPC1 (0.45) | NPC1RAB9AHPGDERCC5FEN1 | |
| SCHEMBL10358883 | 0.85 | ALDH1A1 (0.40) | RAB9AHPGDLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL10358881 | 0.85 | ALDH1A1 (0.40) | RAB9AHPGDLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL1426456 | 0.84 | NPC1 (0.44) | NPC1RAB9AHPGDERCC5FEN1 | |
| SCHEMBL1426457 | 0.84 | NPC1 (0.44) | NPC1RAB9AHPGDERCC5FEN1 | |
| SCHEMBL8461319 | 0.84 | NPC1 (0.44) | NPC1RAB9AHPGDERCC5FEN1 | |
| SCHEMBL6265289 | 0.84 | ERCC5 (0.46) | NPC1RAB9AHPGDERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162945-A | Process for preparing 2-(2-methylphenyl)-3-methoxyacrylic acid methylester | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-19 | — | — | US | claimed |
| US-5898081-A | Chemical process | ZENECA LIMITED (GB) | 1999-04-27 | — | — | US | claimed |
| EP-0656880-B1 | CHEMICAL PROCESS | ZENECA LTD (GB) | 1997-10-15 | — | — | EP | claimed |
| US-9422254-B2 | Methoxyacrylate-based fungicide and methods for preparing and using the same | Central China Normal University (CN) | 2016-08-23 | — | — | US | disclosed |
| CN-101906042-B | Separation and purification method and device of alpha-o-methyl phenyl-beta-methoxyl methyl acrylate | Zhejiang hetian chemical co ltd | 2013-11-13 | — | — | CN | disclosed |
| CN-101906042-B | Separation and purification method and device of alpha-o-methyl phenyl-beta-methoxyl methyl acrylate | Zhejiang hetian chemical co ltd | 2013-11-13 | — | — | CN | disclosed |
| EP-2301925-A1 | A METHOXYL ACRYLIC ESTER FUNGICIDE, THE PREPARATION METHOD AND USES THEREOF | Huazhong Normal University (CN) | 2011-03-30 | — | — | EP | disclosed |
| CN-101906042-A | Separation and purification method and device of alpha-o-methyl phenyl-beta-methoxyl methyl acrylate | Zhejiang hetian chemical co ltd | 2010-12-08 | — | — | CN | disclosed |
| CN-101906042-A | Separation and purification method and device of alpha-o-methyl phenyl-beta-methoxyl methyl acrylate | Zhejiang hetian chemical co ltd | 2010-12-08 | — | — | CN | disclosed |
| US-20100292285-A1 | METHOXYACRYLATE-BASED FUNGICIDE AND METHODS FOR PREPARING AND USING THE SAME | Central China Normal University (CN) | 2010-11-18 | — | — | US | disclosed |
| US-20060287527-A1 | Process for producing acrylic acid derivative | NIPPON SODA CO., LTD. (JP) | 2006-12-21 | — | — | US | disclosed |
| EP-0331966-A1 | Substituted acrylic-acid esters | BAYER AG (DE) | 1989-09-13 | — | — | EP | disclosed |
| US-4822908-A | Substituted acrylates and fungicides containing same | BASF AKTIENGESELLSCHAFT (DE) | 1989-04-18 | — | — | US | disclosed |
| US-4782177-A | AGRICULTURE | BASF AKTIENGESELLSCHAFT (DE) | 1988-11-01 | — | — | US | disclosed |
| EP-0278595-A2 | Fungicides | ZENECA LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |
| US-4723034-A | Stilbene derivatives, and fungicides which contain these compounds | BASF AKTIENGESELLSCHAFT (DE) | 1988-02-02 | — | — | US | disclosed |
| EP-0251082-A2 | Substituted acrylic acid esters and fungicides containing these compounds | BASF Aktiengesellschaft (DE) | 1988-01-07 | — | — | EP | disclosed |
| EP-0229974-A1 | Acrylic acid derivatives and fungicides containing them | BASF Aktiengesellschaft (DE) | 1987-07-29 | — | — | EP | disclosed |
| EP-0226917-A1 | Acrylic acid esters and fungicides containing these compounds | BASF Aktiengesellschaft (DE) | 1987-07-01 | — | — | EP | disclosed |
| EP-0203606-A2 | Derivatives of stilbene and fungicides containing these compounds | BASF Aktiengesellschaft (DE) | 1986-12-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292285-A1 | METHOXYACRYLATE-BASED FUNGICIDE AND METHODS FOR PREPARING AND USING THE SAME | SPOUT1, CDY1; CDY1B, MANBA | NPC1 2932/4885RAB9A 640/4885HPGD 4817/4885 |
| US-20060287527-A1 | Process for producing acrylic acid derivative | APEH, HAAO, ASNS | NPC1 3447/4885RAB9A 715/4885HPGD 1416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.