Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5998811 | 1.00 | NPC1 (0.45) | NPC1RAB9AHPGDERCC5FEN1 | |
| SCHEMBL1426457 | 0.87 | NPC1 (0.44) | NPC1RAB9AHPGDERCC5FEN1 | |
| SCHEMBL8461319 | 0.87 | NPC1 (0.44) | NPC1RAB9AHPGDERCC5FEN1 | |
| SCHEMBL1426456 | 0.87 | NPC1 (0.44) | NPC1RAB9AHPGDERCC5FEN1 | |
| SCHEMBL1426474 | 0.86 | NPC1 (0.43) | NPC1RAB9AHPGDERCC5FEN1 | |
| SCHEMBL5998808 | 0.86 | NPC1 (0.43) | NPC1RAB9AHPGDERCC5FEN1 | |
| SCHEMBL1426471 | 0.86 | NPC1 (0.43) | NPC1RAB9AHPGDERCC5FEN1 | |
| SCHEMBL935204 | 0.82 | KMT2A (0.53) | NPC1RAB9ALMNASMN1; SMN2KMT2A | |
| SCHEMBL2356853 | 0.82 | RAB9A (0.40) | NPC1RAB9AHPGDERCC5FEN1 | |
| SCHEMBL2985717 | 0.81 | LMNA (0.58) | NPC1HPGDLMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169958-A | Reacting, 3-amino-2-propen-1-ones with magnesium halide in solvent | BASF AKTIENGESELLSCHAFT (DE) | 1992-12-08 | — | — | US | disclosed |