SCHEMBL1426484

SCHEMBL1426484

C=C(C)C(=O)OOc1ccc(C[C@H](N)C(=O)O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 1/20 0.53
ITGA2B P08514 1/20 0.53
SLC7A5 Q01650 3/20 0.51
PTPN1 P18031 2/20 0.51
PTGS1 P23219 3/20 0.50
ALPI P09923 1/20 0.50
PKM P14618 1/20 0.50
XIAP P98170 1/20 0.50
TPH1 P17752 3/20 0.44
GRB2 P62993 1/20 0.44
ALOX15 P16050 3/20 0.44
HIF1A Q16665 3/20 0.44
KDM4E B2RXH2 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
USP2 O75604 1/20 0.44
EGFR P00533 1/20 0.44
LCK P06239 1/20 0.44
FYN P06241 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
HTR2A P28223 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5841274 1.00 ITGB3 (0.53) ITGB3ITGA2BSLC7A5PTPN1PTGS1
SCHEMBL3266739 0.89 ITGB3 (0.41) ITGB3ITGA2BSLC7A5PTPN1PTGS1
SCHEMBL345967 0.85 SLC7A5 (0.54) ITGB3ITGA2BSLC7A5PTPN1PTGS1
SCHEMBL18812870 0.85 SLC7A5 (0.54) ITGB3ITGA2BSLC7A5PTPN1PTGS1
SCHEMBL1018596 0.84 SLC7A5 (0.49) ITGB3ITGA2BSLC7A5PTPN1KDM4E
SCHEMBL6522472 0.84 SLC7A5 (0.49) ITGB3ITGA2BSLC7A5PTPN1PTGS1
SCHEMBL21314247 0.81 SLC7A5 (0.53) ITGB3ITGA2BSLC7A5PTPN1PTGS1
SCHEMBL20335056 0.80 ITGB3 (0.60) ITGB3ITGA2BSLC7A5PTPN1PTGS1
SCHEMBL1015911 0.80 ITGB3 (0.48) ITGB3ITGA2BKDM4EKMT2ALMNA
SCHEMBL5843022 0.80 ITGB3 (0.43) ITGB3ITGA2BKDM4ELDHAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240216229-A1 SELF-ADHESIVE FISSURE SEALANT KULZER GMBH (DE) 2024-07-04 US claimed
US-7115674-B2 Dental self-curing resin cement compositions DENTKIST, INC. (KR) 2006-10-03 US claimed
US-20050049326-A1 Dental self-curing resin cement compositions DENTKIST, INC. (KR) 2005-03-03 US claimed
US-20040176496-A1 Light-curing dental adhesive compositions DENTKIST, INC. (KR) 2004-09-09 US claimed
US-20240216229-A1 SELF-ADHESIVE FISSURE SEALANT KULZER GMBH (DE) 2024-07-04 US disclosed
EP-3658065-B1 MICRO-APPLICATOR FOR USE WITH DENTAL ADHESIVES KULZER & CO GMBH (DE) 2023-07-26 EP disclosed
EP-3415539-B1 POLYMERIZABLE COMPOSITION AND KIT THEREOF, AND POLYMERIZATION INITIATOR SUN MEDICAL CO LTD (JP) 2022-03-30 EP disclosed
US-11130864-B2 Polymerizable composition and kit, and polymerization initiator SUN MEDICAL CO., LTD. (JP) 2021-09-28 US disclosed
EP-3835289-A1 SULFUR-CONTAINING POLYMERIZABLE MONOMER AND USE THEREOF Sun Medical Co., Ltd. (JP) 2021-06-16 EP disclosed
US-20200268483-A1 MICRO APPLICATOR FOR USE WITH DENTAL ADHESIVES KULZER GMBH (DE) 2020-08-27 US disclosed
US-20200263024-A1 COMPOSITE PARTICLES, KIT, MATERIAL, AND METHOD FOR PRODUCING COMPOSITE PARTICLES SUN MEDICAL CO., LTD. (JP) 2020-08-20 US disclosed
EP-3689945-A1 COMPOSITE PARTICLES, KIT, MATERIAL AND METHOD FOR PRODUCING COMPOSITE PARTICLES Sun Medical Co., Ltd. (JP) 2020-08-05 EP disclosed
US-5866631-A POLYMERIZABLE MONOMER CONTAINING AN ACIDIC GROUP, WATER, ARYL BORATE AND TRANSITION METAL COMPOUND. TOKUYAMA CORPORATION (JP) 1999-02-02 US disclosed
US-5766328-A Dental composition for relieving dentin hypersensitivity SUN MEDICAL CO., LTD. (JP) 1998-06-16 US disclosed
EP-0811368-A1 DENTAL PRIMER COMPOSITION AND POLYMERIZATION CATALYST TOKUYAMA CORPORATION (JP) 1997-12-10 EP disclosed
US-5587406-A APPLYING CURABLE PRIMER COMPOSITION COMPRISING POLYMERIZABLE MONOMER HAVING ACID GROUP AND POLYMERIZABLE MONOMER HAVING HYDROXYL GROUP AND POLYMERIZATION INITIATOR TO TOOTH SUN MEDICAL CO., LTD. (JP) 1996-12-24 US disclosed
EP-0744171-A1 DENTAL COMPOSITION FOR HYPERSENSITIVE DENTIN SUN MEDICAL CO., LTD. (JP) 1996-11-27 EP disclosed
EP-0721773-A2 Dental composition for relieving dentin hypersensitivity SUN MEDICAL CO., LTD. (JP) 1996-07-17 EP disclosed
US-5530038-A CONTAINING UNSATURATED MONOMER WITH ACIDIC GROUP, UNSATURATED MONOMER WITH HYDROXYL GROUP, POLYMERIZATION INITIATOR, AMINE COMPOUND, ZIRCONIUM OXIDE AND ORGANIC COMPOSITE FILLERS SUN MEDICAL CO., LTD. (JP) 1996-06-25 US disclosed
US-5264513-A Dental adhesive KABUSHIKI KAISHA SHOFU (JP) 1993-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11130864-B2 Polymerizable composition and kit, and polymerization initiator KIT, MCM7, EPHA7 ITGB3 2194/4885ITGA2B 887/4885SLC7A5 2750/4885
US-20040176496-A1 Light-curing dental adhesive compositions HBG2, GRIN2A, HBG1 ITGB3 54/4885ITGA2B 33/4885SLC7A5 4000/4885
US-20240216229-A1 SELF-ADHESIVE FISSURE SEALANT ESD, GFER, FUS ITGB3 878/4885ITGA2B 323/4885SLC7A5 529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.