SCHEMBL1015911

SCHEMBL1015911

C=C(C)C(=O)N[C@@H](Cc1ccc(OOC(=O)C(=C)C)cc1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 6/20 0.48
ITGA2B P08514 6/20 0.48
KDM4A O75164 2/20 0.46
KDM4E B2RXH2 1/20 0.46
TGFBR1 P36897 1/20 0.46
PPARG P37231 3/20 0.44
KMT2A Q03164 1/20 0.42
FPR2 P25090 1/20 0.42
MME P08473 1/20 0.41
ACE P12821 1/20 0.41
CPA1 P15085 1/20 0.41
ACE2 Q9BYF1 1/20 0.41
CA2 P00918 1/20 0.41
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1018596 0.90 SLC7A5 (0.49) ITGB3ITGA2BKDM4AKDM4EPPARG
SCHEMBL9418255 0.87 TGFBR1 (0.48) ITGB3ITGA2BKDM4AKDM4ETGFBR1
SCHEMBL5843022 0.85 ITGB3 (0.43) ITGB3ITGA2BKDM4AKDM4EPPARG
SCHEMBL11035787 0.85 ITGB3 (0.43) ITGB3ITGA2BKDM4AKDM4EPPARG
SCHEMBL15947342 0.82 ITGB3 (0.53) ITGB3ITGA2BKDM4ATGFBR1PPARG
SCHEMBL5841274 0.80 ITGB3 (0.53) ITGB3ITGA2BKDM4EPPARGKMT2A
SCHEMBL1426484 0.80 ITGB3 (0.53) ITGB3ITGA2BKDM4EPPARGKMT2A
SCHEMBL346687 0.80 FOLH1 (0.59) TGFBR1MMEACECPA1ACE2
SCHEMBL8021425 0.80 FOLH1 (0.59) TGFBR1MMEACECPA1ACE2
SCHEMBL346221 0.80 TGFBR1 (0.57) TGFBR1FPR2MMEACECPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220169844-A1 COMPOSITE PARTICLES, KIT, MATERIAL, AND METHOD FOR PRODUCING COMPOSITE PARTICLES SUN MEDICAL CO., LTD. (JP) 2022-06-02 US disclosed
EP-3415539-B1 POLYMERIZABLE COMPOSITION AND KIT THEREOF, AND POLYMERIZATION INITIATOR SUN MEDICAL CO LTD (JP) 2022-03-30 EP disclosed
US-11130864-B2 Polymerizable composition and kit, and polymerization initiator SUN MEDICAL CO., LTD. (JP) 2021-09-28 US disclosed
US-20200263024-A1 COMPOSITE PARTICLES, KIT, MATERIAL, AND METHOD FOR PRODUCING COMPOSITE PARTICLES SUN MEDICAL CO., LTD. (JP) 2020-08-20 US disclosed
EP-3689945-A1 COMPOSITE PARTICLES, KIT, MATERIAL AND METHOD FOR PRODUCING COMPOSITE PARTICLES Sun Medical Co., Ltd. (JP) 2020-08-05 EP disclosed
US-20190040261-A1 POLYMERIZABLE COMPOSITION AND KIT, AND POLYMERIZATION INITIATOR SUN MEDICAL CO., LTD. (JP) 2019-02-07 US disclosed
EP-3415539-A1 POLYMERIZABLE COMPOSITION AND KIT THEREOF, AND POLYMERIZATION INITIATOR SUN MEDICAL CO., LTD. (JP) 2018-12-19 EP disclosed
EP-2272486-A1 EASILY REMOVABLE CURABLE COMPOSITION FOR DENTAL USE SUN MEDICAL CO., LTD. (JP) 2011-01-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11130864-B2 Polymerizable composition and kit, and polymerization initiator KIT, MCM7, EPHA7 ITGB3 2194/4885ITGA2B 887/4885KDM4A 1599/4885
US-20190040261-A1 POLYMERIZABLE COMPOSITION AND KIT, AND POLYMERIZATION INITIATOR KIT, MCM7, EPHA7 ITGB3 2194/4885ITGA2B 887/4885KDM4A 1599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.