SCHEMBL1426567

SCHEMBL1426567

C=CC(=O)C(C=C)N1CCNCC1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 6/20 0.35
F13A1 P00488 1/20 0.34
TGM2 P21980 1/20 0.34
TGM1 P22735 1/20 0.34
CHRM5 P08912 1/20 0.33
CHRM3 P20309 1/20 0.33
CA2 P00918 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA9 Q16790 1/20 0.32
CHKA P35790 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP19A1 P11511 1/20 0.31
CHRNB2 P17787 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA4 P43681 1/20 0.31
CHRNB3 Q05901 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11130889 0.78 OPRD1 (0.36) OPRD1F13A1TGM2TGM1CA2
SCHEMBL1286434 0.73 SIGMAR1 (0.40) OPRD1CHRM5CHRM3SIGMAR1
SCHEMBL28201826 0.70 SIGMAR1 (0.44) CHRM5CHRM3SIGMAR1
SCHEMBL2577695 0.69 MEN1 (0.33) CA2MEN1KMT2ACHKACYP2D6
SCHEMBL10832743 0.69 MEN1 (0.33) MEN1KMT2ACYP2D6CYP19A1
SCHEMBL861270 0.69 MEN1 (0.33) MEN1KMT2ACYP2D6CYP19A1
SCHEMBL3861429 0.67 MEN1 (0.32) MEN1KMT2ACYP2D6CYP19A1
SCHEMBL7135901 0.67 MEN1 (0.32) MEN1KMT2ACYP2D6CYP19A1
SCHEMBL28450486 0.67 CHRM5 (0.34) OPRD1F13A1TGM2TGM1CHRM5
SCHEMBL730166 0.66 TSHR (0.47) OPRD1F13A1TGM2TGM1CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110066597-A A kind of dedicated silicone hydrogels antifouling paint of fishing gear, its preparation method and application 中国科学院宁波材料技术与工程研究所 2019-07-30 CN claimed
CN-107522875-A Hydrogel, its preparation method and the application of Nano silver grain crosslinking 中国科学院宁波材料技术与工程研究所 2017-12-29 CN claimed
EP-2231858-B1 PATTERNED CELL SHEETS AND A METHOD FOR PRODUCTION OF THE SAME KONINKL PHILIPS NV (NL) 2015-11-04 EP claimed
US-9675417-B2 Safe ablation KONINKLIJKE PHILIPS N.V. (NL) 2017-06-13 US disclosed
US-9267109-B2 Patterned cell sheets and a method for production of the same KONINKLIJKE PHILIPS N.V. (NL) 2016-02-23 US disclosed
EP-2320823-B1 SAFE ABLATION KONINKL PHILIPS NV (NL) 2016-01-27 EP disclosed
EP-2231858-B1 PATTERNED CELL SHEETS AND A METHOD FOR PRODUCTION OF THE SAME KONINKL PHILIPS NV (NL) 2015-11-04 EP disclosed
WO-2015038205-A1 SURFACE PLASMON RESONANCE SPECTROSCOPY METHOD TO DETECT RESIDUAL POLYMER FLOCCULANTS IN CELL CULTURE FEED STREAMS EMD MILLIPORE CORPORATION (US) 2015-03-19 WO disclosed
US-8382339-B2 Light output device KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2013-02-26 US disclosed
US-8323221-B2 Tissue temperature indicating element for ultrasound therapy KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2012-12-04 US disclosed
US-8244078-B2 Hydrogel based sensor probe for detecting an environmental state KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2012-08-14 US disclosed
WO-2008132651-A1 MICROMIXER AND/OR MICROREACTOR WITH ACTIVE FLOW CONTROLLING MEANS KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2008-11-06 WO disclosed
WO-2008117223-A1 A MICRO-FLUIDIC DEVICE COMPRISING AN INTERNAL ACTUATION ELEMENT KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2008-10-02 WO disclosed
EP-1972376-A1 A micro-fluidic device based upon active matrix principles Koninklijke Philips Electronics N.V. (NL) 2008-09-24 EP disclosed
EP-1966599-A1 MAGNETOCHEMICAL SENSOR Koninklijke Philips Electronics N.V. (NL) 2008-09-10 EP disclosed
WO-2008090501-A1 PROCESS FOR TREATING CULTURED CELLS KONINKLIJKE PHILIPS ELECTRONICS N. V. (NL) 2008-07-31 WO disclosed
WO-2008068676-A1 BIOTECHNOLOGICAL DEVICE INCLUDING A STRUCTURED HYDROGEL PERMEATION LAYER KONINKLIJKE PHILIPS ELECTRONICS N. V. (NL) 2008-06-12 WO disclosed
WO-2008068678-A1 BIOTECHNOLOGICAL DEVICE INCLUDING AN ACTUATION MEANS FOR CHANGING THE MOBILITY OF PRESELECTED BIOMOLECULES KONINKLIJKE PHILIPS ELECTRONICS N. V. (NL) 2008-06-12 WO disclosed
WO-2007135651-A1 A BIOSENSOR SOLID SUBSTRATE WITH INTEGRATED TEMPERATURE CONTROL AND A METHOD TO MAKE THE SAME KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2007-11-29 WO disclosed
WO-2007072243-A1 MAGNETOCHEMICAL SENSOR KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2007-06-28 WO disclosed