Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14287142 | 0.82 | MAPT (0.41) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL3254574 | 0.79 | LMNA (0.52) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL15353518 | 0.78 | MAPT (0.45) | MAPTLMNAGSTM2ALDH1A1MEN1 | |
| SCHEMBL16712117 | 0.78 | MAPT (0.52) | MAPTTXNRD1LMNAGSTP1GSTM2 | |
| SCHEMBL2067384 | 0.77 | RAB9A (0.48) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL5122680 | 0.76 | MAPT (0.36) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL5971893 | 0.75 | NUDT1 (0.48) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL2018202 | 0.75 | CYP1A2 (0.53) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL30051515 | 0.74 | POLB (0.40) | MAPTGSTP1GSTM2ALDH1A1MEN1 | |
| SCHEMBL10697343 | 0.74 | MAPT (0.73) | MAPTTXNRD1LMNAGSTP1GSTM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058383-A1 | Androgen Receptor Modulators | KARO BIO AB (SE) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058383-A1 | Androgen Receptor Modulators | NR5A1, ESRRA, AR | MAPT 3258/4885TXNRD1 562/4885LMNA 2695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.