SCHEMBL1426752

SCHEMBL1426752

CC(C)C(=CC(=O)O)C(N)=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 2/20 0.36
GABRD O14764 2/20 0.36
GABRA1 P14867 2/20 0.36
GABRB1 P18505 2/20 0.36
GABRG2 P18507 2/20 0.36
GABRB3 P28472 2/20 0.36
GABRA5 P31644 2/20 0.36
GABRA3 P34903 2/20 0.36
GABRA2 P47869 2/20 0.36
GABRB2 P47870 2/20 0.36
GABRA4 P48169 2/20 0.36
GABRE P78334 2/20 0.36
GABRA6 Q16445 2/20 0.36
GABRG1 Q8N1C3 2/20 0.36
GABRG3 Q99928 2/20 0.36
GABRQ Q9UN88 2/20 0.36
LDHA P00338 1/20 0.32
LDHB P07195 1/20 0.32
KDM1A O60341 1/20 0.32
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28760214 1.00 GABRP (0.36) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL28760215 0.82 POLB (0.35)
SCHEMBL28875766 0.81
SCHEMBL346751 0.79 KDM4E (0.33) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL346752 0.79 KDM4E (0.33) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL2416426 0.79 KDM4E (0.33) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL28808090 0.77 KDM1A (0.32) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL28139155 0.77 LDHA (0.33) LDHALDHB
Hydrochloric Acid SCHEMBL9168486 0.77 KDM1A (0.32) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL25867915 0.77 KDM4E (0.37) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2231858-B1 PATTERNED CELL SHEETS AND A METHOD FOR PRODUCTION OF THE SAME KONINKL PHILIPS NV (NL) 2015-11-04 EP claimed
US-9675417-B2 Safe ablation KONINKLIJKE PHILIPS N.V. (NL) 2017-06-13 US disclosed
EP-2522679-B1 PHENYLBORONIC ACID MONOMER AND PHENYLBORONIC ACID POLYMER NAT INST FOR MATERIALS SCIENCE (JP) 2016-07-13 EP disclosed
US-9267109-B2 Patterned cell sheets and a method for production of the same KONINKLIJKE PHILIPS N.V. (NL) 2016-02-23 US disclosed
EP-2320823-B1 SAFE ABLATION KONINKL PHILIPS NV (NL) 2016-01-27 EP disclosed
EP-2231858-B1 PATTERNED CELL SHEETS AND A METHOD FOR PRODUCTION OF THE SAME KONINKL PHILIPS NV (NL) 2015-11-04 EP disclosed
US-8382339-B2 Light output device KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2013-02-26 US disclosed
US-8323221-B2 Tissue temperature indicating element for ultrasound therapy KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2012-12-04 US disclosed
EP-2522679-A1 PHENYLBORONIC ACID MONOMER AND PHENYLBORONIC ACID POLYMER National Institute for Materials Science (JP) 2012-11-14 EP disclosed
US-20120283403-A1 Phenylboronic Acid Monomer and Phenylboronic Acid Polymer NATIONAL INSTITUTE FOR MATERIALS SCIENCE (JP) 2012-11-08 US disclosed
WO-2008135899-A1 BIO-RECOGNITION SENSOR WITH ACTUATION DEVICE KONINKLIJKE PHILIPS ELECTRONICS N. V. (NL) 2008-11-13 WO disclosed
WO-2008132651-A1 MICROMIXER AND/OR MICROREACTOR WITH ACTIVE FLOW CONTROLLING MEANS KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2008-11-06 WO disclosed
WO-2008117223-A1 A MICRO-FLUIDIC DEVICE COMPRISING AN INTERNAL ACTUATION ELEMENT KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2008-10-02 WO disclosed
EP-1972376-A1 A micro-fluidic device based upon active matrix principles Koninklijke Philips Electronics N.V. (NL) 2008-09-24 EP disclosed
EP-1966599-A1 MAGNETOCHEMICAL SENSOR Koninklijke Philips Electronics N.V. (NL) 2008-09-10 EP disclosed
WO-2008090501-A1 PROCESS FOR TREATING CULTURED CELLS KONINKLIJKE PHILIPS ELECTRONICS N. V. (NL) 2008-07-31 WO disclosed
WO-2008068678-A1 BIOTECHNOLOGICAL DEVICE INCLUDING AN ACTUATION MEANS FOR CHANGING THE MOBILITY OF PRESELECTED BIOMOLECULES KONINKLIJKE PHILIPS ELECTRONICS N. V. (NL) 2008-06-12 WO disclosed
WO-2008068676-A1 BIOTECHNOLOGICAL DEVICE INCLUDING A STRUCTURED HYDROGEL PERMEATION LAYER KONINKLIJKE PHILIPS ELECTRONICS N. V. (NL) 2008-06-12 WO disclosed
WO-2007135651-A1 A BIOSENSOR SOLID SUBSTRATE WITH INTEGRATED TEMPERATURE CONTROL AND A METHOD TO MAKE THE SAME KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2007-11-29 WO disclosed
WO-2007072243-A1 MAGNETOCHEMICAL SENSOR KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2007-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120283403-A1 Phenylboronic Acid Monomer and Phenylboronic Acid Polymer MAPK13, PAH, MAP3K13 GABRP 88/4885GABRD 871/4885GABRA1 80/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.