Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11686593 | 0.81 | GFER (0.59) | ALDH1A1KDM4EGFERUSP2ESR1 | |
| SCHEMBL15846794 | 0.80 | BRD4 (0.42) | BRD4ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL2362636 | 0.78 | MAPT (0.43) | BRD4GAAALDH1A1KDM4EMAPT | |
| SCHEMBL13162979 | 0.77 | KMT2A (0.52) | BRD4GAAALDH1A1KDM4EMAPT | |
| SCHEMBL14267652 | 0.76 | MAPT (0.56) | BRD4GAAALDH1A1KDM4EMAPT | |
| SCHEMBL25783176 | 0.73 | PRKCA (0.49) | GAAALDH1A1KDM4EMAPTGFER | |
| SCHEMBL29778138 | 0.72 | GAA (0.41) | BRD4GAAALDH1A1KDM4EMAPT | |
| SCHEMBL13196859 | 0.68 | BRD4 (0.47) | BRD4GAAALDH1A1KDM4EMAPT | |
| SCHEMBL5579236 | 0.68 | TP53 (0.51) | GAAALDH1A1KDM4EMAPTGFER | |
| SCHEMBL10540887 | 0.68 | TSHR (0.47) | BRD4ALDH1A1KDM4EHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957222-B | Compound and preparation method and application thereof | 内蒙古民族大学 | 2023-08-15 | — | — | CN | disclosed |
| CN-114957222-A | Compound and preparation method and application thereof | 内蒙古民族大学 | 2022-08-30 | — | — | CN | disclosed |