Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14607774 | 0.89 | THRB (0.35) | THRBMAPK1HIF1ATDP1MEN1 | |
| SCHEMBL14268589 | 0.85 | MEN1 (0.37) | THRBMAPK1HIF1ATDP1MEN1 | |
| SCHEMBL14268573 | 0.83 | THRB (0.38) | THRBMAPK1HIF1ATDP1MEN1 | |
| SCHEMBL16263283 | 0.81 | THRB (0.34) | THRBMAPK1HIF1ATDP1MEN1 | |
| SCHEMBL23774924 | 0.81 | THRB (0.34) | THRBMAPK1HIF1ATDP1MEN1 | |
| SCHEMBL14268570 | 0.80 | THRB (0.33) | THRBMAPK1HIF1ATDP1MEN1 | |
| SCHEMBL14268578 | 0.79 | HTT (0.36) | THRBMAPK1HIF1ATDP1MEN1 | |
| SCHEMBL14268588 | 0.78 | TDP1 (0.38) | MAPK1TDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12387272 | 0.78 | TDP1 (0.41) | THRBMAPK1HIF1ATDP1MEN1 | |
| SCHEMBL23945091 | 0.78 | THRB (0.32) | THRBMAPK1HIF1ATDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329289-B2 | Use of triarylmethane derivatives as direct dyes in a dye composition, composition and implementation process | L'Oréal, S.A. (FR) | 2008-02-12 | — | — | US | disclosed |