SCHEMBL14273149

SCHEMBL14273149

CCN1/C(=C2\SC(=S)NC2=O)Sc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 10/20 1.00
▸ ALDH1A1 P00352 9/20 1.00
▸ TDP1 Q9NUW8 2/20 1.00
▸ GFER P55789 1/20 1.00
▸ MEN1 O00255 13/20 0.64
▸ KMT2A Q03164 13/20 0.64
▸ HPGD P15428 3/20 0.62
▸ ALOX15 P16050 2/20 0.62
▸ ALOX12 P18054 2/20 0.62
▸ CASP1 P29466 2/20 0.62
▸ HSD17B10 Q99714 2/20 0.62
▸ PKM P14618 1/20 0.62
▸ SMN1; SMN2 Q16637 2/20 0.57
▸ NPSR1 Q6W5P4 1/20 0.56
▸ POLB P06746 4/20 0.56
▸ NPC1 O15118 2/20 0.53
▸ MMP13 P45452 1/20 0.48
▸ GAA P10253 1/20 0.47
▸ APEX1 P27695 1/20 0.46
▸ LMNA P02545 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9651271 0.82 ALDH1A1 (0.70) MAPTALDH1A1TDP1GFERMEN1
SCHEMBL9651277 0.82 ALDH1A1 (0.70) MAPTALDH1A1TDP1GFERMEN1
SCHEMBL7019338 0.78 MEN1 (1.00) MAPTALDH1A1TDP1GFERMEN1
SCHEMBL10036060 0.78 MEN1 (1.00) MAPTALDH1A1TDP1GFERMEN1
SCHEMBL8887899 0.78 MEN1 (1.00) MAPTALDH1A1TDP1GFERMEN1
SCHEMBL10778714 0.75 MAPT (0.62) MAPTALDH1A1TDP1GFERMEN1
SCHEMBL14443291 0.74 MEN1 (0.65) MAPTALDH1A1TDP1GFERMEN1
SCHEMBL14443298 0.73 MEN1 (0.64) MAPTALDH1A1TDP1GFERMEN1
SCHEMBL14273142 0.73 MEN1 (0.64) MAPTALDH1A1TDP1GFERMEN1
SCHEMBL11278635 0.73 MEN1 (1.00) MAPTALDH1A1TDP1GFERMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7335466-B2 Silver salt photothermographic dry imaging material, image recording method and image forming method for the same KONICA MINOLTA HOLDINGS, INC. (JP) 2008-02-26 — — US disclosed
US-7335466-B2 Silver salt photothermographic dry imaging material, image recording method and image forming method for the same KONICA MINOLTA HOLDINGS, INC. (JP) 2008-02-26 — — US disclosed
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