Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4021881 | 0.80 | HRH3 (0.37) | KCNH2KDM4ELMNAUSP2ALDH1A1 | |
| SCHEMBL1120466 | 0.80 | TSHR (0.44) | KDM4ELMNAUSP2ALDH1A1MMP9 | |
| SCHEMBL21437239 | 0.78 | MMP9 (0.36) | KCNH2KDM4ELMNAUSP2ALDH1A1 | |
| SCHEMBL22530705 | 0.78 | ALDH1A1 (0.43) | KDM4ELMNAALDH1A1GAA | |
| SCHEMBL3258334 | 0.76 | CA2 (0.50) | KCNH2KDM4ELMNAUSP2ALDH1A1 | |
| SCHEMBL2075495 | 0.76 | ALDH1A1 (0.45) | KDM4ELMNAUSP2ALDH1A1MMP9 | |
| SCHEMBL1162383 | 0.74 | HRH3 (0.47) | KCNH2KDM4ELMNAUSP2ALDH1A1 | |
| SCHEMBL20301886 | 0.73 | HTR2A (0.32) | KCNH2 | |
| SCHEMBL8427958 | 0.73 | AOC3 (0.43) | AOC3KCNH2KDM4ELMNAALDH1A1 | |
| SCHEMBL18496716 | 0.72 | MAPK1 (0.49) | KDM4ELMNAALDH1A1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7320973-B2 | Dihydrodiaryloxazepine derivative and pharmaceutical composition containing the same | AJINOMOTO CO., INC. (JP) | 2008-01-22 | — | — | US | disclosed |