Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.59 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3357146 | 0.93 | GAA (0.55) | LMNAGAAABCC4TSHRPTGS1 | |
| SCHEMBL27594421 | 0.92 | HPGD (0.55) | LMNAGAAABCC4TSHRPTGS1 | |
| SCHEMBL3358287 | 0.91 | CYP4F2 (0.59) | LMNAGAAABCC4TSHRPTGS1 | |
| SCHEMBL4675 | 0.88 | ALDH1A1 (0.62) | LMNATSHRCYP4F2CYP4A11KMT2A | |
| SCHEMBL1870609 | 0.88 | ALDH1A1 (0.62) | LMNATSHRCYP4F2CYP4A11KMT2A | |
| Benzene SCHEMBL28096336 | 0.88 | ALDH1A1 (0.62) | LMNATSHRCYP4F2CYP4A11KMT2A | |
| SCHEMBL7236732 | 0.87 | FFAR1 (0.61) | SMN1; SMN2NPC1RAB9AALDH1A1FFAR1 | |
| SCHEMBL6801321 | 0.87 | LMNA (0.56) | LMNAGAAABCC4TSHRPTGS1 | |
| Hydrochloric Acid SCHEMBL9268979 | 0.86 | ALDH1A1 (0.61) | LMNATSHRCYP4F2CYP4A11KMT2A | |
| Ethane SCHEMBL10923525 | 0.86 | ALDH1A1 (0.61) | LMNATSHRCYP4F2CYP4A11KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106431911-B | Preparation and purification method of 4-felbinac | 黄石市利福达医药化工有限公司 | 2021-05-28 | — | — | CN | claimed |
| US-4046814-A | Preparation of diketones | WRIGHT STATE UNIVERSITY (US) | 1977-09-06 | — | — | US | claimed |
| US-11485721-B2 | Method for the metal-free preparation of a biaryl by a photosplicing reaction and their uses | Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. Hans-Knöll-Institut (DE) | 2022-11-01 | — | — | US | disclosed |
| US-11485721-B2 | Method for the metal-free preparation of a biaryl by a photosplicing reaction and their uses | Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. Hans-Knöll-Institut (DE) | 2022-11-01 | — | — | US | disclosed |
| CN-106431911-B | Preparation and purification method of 4-felbinac | 黄石市利福达医药化工有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-106431911-B | Preparation and purification method of 4-felbinac | 黄石市利福达医药化工有限公司 | 2021-05-28 | — | — | CN | disclosed |
| US-20200339529-A1 | METHOD FOR THE METAL-FREE PREPARATION OF A BIARYL BY A PHOTOSPLICING REACTION AND THEIR USES | LEIBNIZ-INSTITUT FÜR NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE E.V. HANS-KNÖLL-INSTITUT (HKI) (DE) | 2020-10-29 | — | — | US | disclosed |
| US-20200339529-A1 | METHOD FOR THE METAL-FREE PREPARATION OF A BIARYL BY A PHOTOSPLICING REACTION AND THEIR USES | LEIBNIZ-INSTITUT FÜR NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE E.V. HANS-KNÖLL-INSTITUT (HKI) (DE) | 2020-10-29 | — | — | US | disclosed |
| EP-3713910-A1 | METHOD FOR THE METAL-FREE PREPARATION OF A BIARYL BY A PHOTOSPLICING REACTION AND THEIR USES | Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e.V. -Hans-Knöll-Institut- (HKI) (DE) | 2020-09-30 | — | — | EP | disclosed |
| US-10414728-B2 | Use of tetrahydropyridines in the treatment of sodium channel related disease and disorders | CENNERV PHARMA (S) PTE LTD (SG) | 2019-09-17 | — | — | US | disclosed |
| US-10414728-B2 | Use of tetrahydropyridines in the treatment of sodium channel related disease and disorders | CENNERV PHARMA (S) PTE LTD (SG) | 2019-09-17 | — | — | US | disclosed |
| CN-1243510-A | Tricyclicbenzo [3] isoindole and benzo (h) isoquinoline | HOFFMANN LA ROCHE (CH) | 2000-02-02 | — | — | CN | disclosed |
| WO-1999031066-A1 | PYRIDONES AS SRC FAMILY SH2 DOMAIN INHIBITORS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1999-06-24 | — | — | WO | disclosed |
| EP-0900197-A1 | BETA-THIOPROPIONYL-AMINOACID DERIVATIVES AND THEIR USE AS BETA-LACTAMASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997030027-A1 | BETA-THIOPROPIONYL-AMINOACID DERIVATIVES AND THEIR USE AS BETA-LACTAMASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 1997-08-21 | — | — | WO | disclosed |
| EP-0564960-A1 | Imidazopyridines as angiotensin II antagonists | MERCK PATENT GmbH (DE) | 1993-10-13 | — | — | EP | disclosed |
| EP-0171084-B1 | PHARMACEUTICAL OIL-IN-WATER TYPE MICRO-EMULSION | LEDERLE (JAPAN) LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |
| US-4647586-A | BIPHENYLACETIC ACID ESTER | LEDERLE (JAPAN), LTD. (JP) | 1987-03-03 | — | — | US | disclosed |
| EP-0171084-A2 | Pharmaceutical oil-in-water type micro-emulsion | LEDERLE (JAPAN) LTD. (JP) | 1986-02-12 | — | — | EP | disclosed |
| US-4046814-A | Preparation of diketones | WRIGHT STATE UNIVERSITY (US) | 1977-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11485721-B2 | Method for the metal-free preparation of a biaryl by a photosplicing reaction and their uses | CBR3, POR, CYP2F1 | LMNA 944/4885GAA 1257/4885ABCC4 2595/4885 |
| US-20200339529-A1 | METHOD FOR THE METAL-FREE PREPARATION OF A BIARYL BY A PHOTOSPLICING REACTION AND THEIR USES | CBR3, POR, CYP2F1 | LMNA 944/4885GAA 1257/4885ABCC4 2595/4885 |
| US-10414728-B2 | Use of tetrahydropyridines in the treatment of sodium channel related disease and disorders | KCND2, KCNJ2, KCNH3 | LMNA 2110/4885GAA 1459/4885ABCC4 372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.