Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | LDHB | P07195 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6740064 | 0.71 | CASP1 (0.32) | POLB | |
| SCHEMBL6423679 | 0.65 | NOTUM (0.36) | POLB | |
| SCHEMBL3556800 | 0.63 | AKR1C3 (0.42) | POLB | |
| SCHEMBL3556523 | 0.63 | GAA (0.44) | POLB | |
| SCHEMBL3555128 | 0.63 | BAZ2B (0.49) | POLB | |
| SCHEMBL6420808 | 0.61 | NPC1 (0.35) | POLB | |
| SCHEMBL27789723 | 0.58 | ADORA3 (0.37) | POLB | |
| SCHEMBL13858295 | 0.57 | ADORA3 (0.33) | POLB | |
| SCHEMBL2046049 | 0.57 | CYP3A4 (0.52) | LDHALDHBPOLBCYP3A4 | |
| SCHEMBL28779999 | 0.56 | KDM4E (0.40) | LDHALDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323488-B2 | Chromogenic enzyme substrates | BURTON MICHAEL | 2008-01-29 | — | — | US | disclosed |