SCHEMBL14280280

SCHEMBL14280280

CCCCc1ccccc1NC(=O)c1ccccc1I

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC16A3 O15427 10/20 0.55
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
POLB P06746 1/20 0.47
PLK1 P53350 3/20 0.45
PLK3 Q9H4B4 3/20 0.45
CFTR P13569 1/20 0.45
PARP1 P09874 1/20 0.45
ABL1 P00519 1/20 0.44
SRC P12931 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylamine SCHEMBL27546412 0.97 SLC16A3 (0.53) SLC16A3MEN1KMT2ATDP1POLB
SCHEMBL4831437 0.94 SLC16A3 (0.60) SLC16A3MEN1KMT2ATDP1POLB
SCHEMBL14546204 0.82 SLC16A3 (0.52) SLC16A3POLBPLK1PLK3
Methylamine SCHEMBL27546410 0.82 SLC16A3 (0.69) SLC16A3KMT2APOLB
Methylamine SCHEMBL27566515 0.82 SMN1; SMN2 (0.52) SLC16A3MEN1KMT2ATDP1
SCHEMBL15552280 0.82 LMNA (0.58) SLC16A3PLK1PLK3
SCHEMBL13645618 0.82 KMT2A (0.49) SLC16A3MEN1KMT2ATDP1CFTR
SCHEMBL14280281 0.81 SMN1; SMN2 (0.54) SLC16A3POLBPLK1PLK3
SCHEMBL16532204 0.81 SLC16A3 (0.61) SLC16A3POLBPLK1PLK3
SCHEMBL9979257 0.81 SLC16A3 (0.54) SLC16A3POLBPLK1PLK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7314958-B2 Phenylbenzamides BAYER CROPSCIENCE AG (DE) 2008-01-01 US disclosed
US-7314958-B2 Phenylbenzamides BAYER CROPSCIENCE AG (DE) 2008-01-01 US disclosed