SCHEMBL4831437

SCHEMBL4831437

CCCCCCc1ccccc1NC(=O)c1ccccc1I

nearest known ligand 0.60

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC16A3 O15427 10/20 0.60
PLK1 P53350 5/20 0.52
PLK3 Q9H4B4 3/20 0.52
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
POLB P06746 1/20 0.45
LIPG Q9Y5X9 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14280280 0.94 SLC16A3 (0.55) SLC16A3PLK1PLK3MEN1KMT2A
Methylamine SCHEMBL27546412 0.92 SLC16A3 (0.53) SLC16A3PLK1PLK3MEN1KMT2A
SCHEMBL15552280 0.85 LMNA (0.58) SLC16A3PLK1PLK3
SCHEMBL14280279 0.82 SLC16A3 (0.55) SLC16A3PLK1PLK3
SCHEMBL15094109 0.81 POLB (0.60) SLC16A3MEN1KMT2APOLBLIPG
SCHEMBL29582053 0.81 POLB (0.60) SLC16A3MEN1KMT2APOLBLIPG
SCHEMBL29581002 0.81 POLB (0.60) SLC16A3MEN1KMT2APOLBLIPG
SCHEMBL15093870 0.81 POLB (0.60) SLC16A3MEN1KMT2APOLBLIPG
SCHEMBL29582084 0.81 POLB (0.60) SLC16A3MEN1KMT2APOLBLIPG
SCHEMBL15093617 0.81 POLB (0.60) SLC16A3MEN1KMT2APOLBLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7314958-B2 Phenylbenzamides BAYER CROPSCIENCE AG (DE) 2008-01-01 US disclosed
US-7314958-B2 Phenylbenzamides BAYER CROPSCIENCE AG (DE) 2008-01-01 US disclosed
US-7314958-B2 Phenylbenzamides BAYER CROPSCIENCE AG (DE) 2008-01-01 US disclosed
US-20060211771-A1 Phenyl benzamides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2006-09-21 US disclosed
EP-1519913-A1 PHENYL BENZAMIDES Bayer CropScience AG (DE) 2005-04-06 EP disclosed
WO-2004005242-A1 PHENYL BENZAMIDES BAYER CROPSCIENCE AG (DE) 2004-01-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060211771-A1 Phenyl benzamides PADI1, PNMT, BRPF3 SLC16A3 4753/4885PLK1 4215/4885PLK3 882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.