Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL611756 | 0.74 | — | — | |
| SCHEMBL22893306 | 0.70 | — | — | |
| SCHEMBL17938008 | 0.67 | TP53 (0.36) | TSHR | |
| SCHEMBL5549439 | 0.67 | TP53 (0.36) | TSHR | |
| SCHEMBL5212996 | 0.66 | — | — | |
| SCHEMBL7109897 | 0.66 | TSHR (0.33) | TSHR | |
| SCHEMBL18976834 | 0.65 | KDM4E (0.30) | — | |
| SCHEMBL13139135 | 0.65 | KDM4E (0.30) | — | |
| SCHEMBL11490831 | 0.65 | TSHR (0.31) | TSHR | |
| SCHEMBL28033169 | 0.65 | LMNA (0.33) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314959-B2 | Amino thiol compounds and compositions for use in conjunction with cancer therapy | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-01-01 | — | — | US | disclosed |
| US-7314959-B2 | Amino thiol compounds and compositions for use in conjunction with cancer therapy | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-01-01 | — | — | US | disclosed |