SCHEMBL5212996

SCHEMBL5212996

CC(=O)SC(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7109897 0.79 TSHR (0.33)
SCHEMBL7161283 0.76
SCHEMBL13987916 0.76
SCHEMBL7161276 0.76
SCHEMBL3071643 0.74 NOS3 (0.40)
SCHEMBL1345278 0.73
SCHEMBL9226713 0.73
SCHEMBL11109816 0.73
SCHEMBL11369585 0.73
SCHEMBL16077445 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1611166-B1 BUILDING SEALANT COMPOSITION BRIDGESTONE CORP (JP) 2007-08-29 EP claimed
US-20240018156-A1 SPIROCYCLIC COMPOUNDS C4 THERAPEUTICS, INC. (US) 2024-01-18 US disclosed
US-20230295081-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. 2023-09-21 US disclosed
US-20230173093-A1 CHARGE VARIANT LINKERS SEAGEN INC (US) 2023-06-08 US disclosed
EP-3953341-A1 NOVEL OXADIAZOLE COMPOUNDS FOR CONTROLLING OR PREVENTING PHYTOPATHOGENIC FUNGI PI Industries Ltd. (IN) 2022-02-16 EP disclosed
WO-2020208511-A1 NOVEL OXADIAZOLE COMPOUNDS FOR CONTROLLING OR PREVENTING PHYTOPATHOGENIC FUNGI PI INDUSTRIES LIMITED (IN) 2020-10-15 WO disclosed
CN-110229333-A A kind of synthetic method of new type polyimide 湘潭大学 2019-09-13 CN disclosed
CN-106519102-B A kind of acrylic acid modified polymer of salt-resistant type and preparation method thereof 广州天赐高新材料股份有限公司 2019-02-01 CN disclosed
US-20170360740-A1 HISTONE DEACETYLASE INHIBITORS DANA-FARBER CANCER INSTITUTE, INC. 2017-12-21 US disclosed
US-9724321-B2 Histone deacetylase inhibitors PRESIDENT & FELLOWS OF HARVARD COLLEGE (US) 2017-08-08 US disclosed
US-7470722-B2 Multicyclic sulfonamide compounds as inhibitors of histone deacetylase for the treatment of disease KALYPSYS, INC. (US) 2008-12-30 US disclosed
US-20080194681-A1 Novel Inhibitors of Histone Deacetylase for the Treatment of Disease KALYPSYS, INC. (US) 2008-08-14 US disclosed
US-20080193983-A1 Quasirandom Structure and Function Guided Synthesis Methods NUEVOLUTION A/S (DK) 2008-08-14 US disclosed
US-20080193983-A1 Quasirandom Structure and Function Guided Synthesis Methods NUEVOLUTION A/S (DK) 2008-08-14 US disclosed
US-7381749-B2 Sulfonamides as inhibitors of histone deacetylase for the treatment of disease KALYPSYS, INC. (US) 2008-06-03 US disclosed
US-7271195-B2 Carbonyl compounds as inhibitors of histone deacetylase for the treatment of disease KALYPSYS, INC. (US) 2007-09-18 US disclosed
US-20070135438-A1 INHIBITORS OF HISTONE DEACETYLASE FOR THE TREATMENT OF DISEASE KALYPSYS, INC. (US) 2007-06-14 US disclosed
US-20070027184-A1 Multicyclic sulfonamide compounds as inhibitors of histone deacetylase for the treatment of disease KALYPSYS, INC. 2007-02-01 US disclosed
CN-1158315-C Process for producing ethylene/olefin interpolymers 伊斯曼化学公司 2004-07-21 CN disclosed
CN-1367800-A Process for producing ethylene/olefin interpolymers EASTMAN CHEM CO (US) 2002-09-04 CN disclosed