SCHEMBL14280407

SCHEMBL14280407

CCCCn1c2ccc(C(C)(C)C)cc2c(=O)c2cc(C(C)(C)C)ccc21

nearest known ligand 0.71

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
RORA P35398 13/20 0.71
RORC P51449 13/20 0.71
RORB Q92753 13/20 0.71
PGR P06401 11/20 0.71
NR1H2 P55055 1/20 0.48
NPC1 O15118 2/20 0.44
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14280384 0.93 PGR (0.74) RORARORCRORBPGRNPC1
SCHEMBL22042197 0.86 RORA (0.63) RORARORCRORBPGR
SCHEMBL22087154 0.86 RORA (0.63) RORARORCRORBPGR
SCHEMBL14280387 0.85 PGR (0.67) RORARORCRORBPGRNPC1
SCHEMBL28320105 0.84 RORA (0.61) RORARORCRORBPGRNR1H2
SCHEMBL29780772 0.84 RORA (0.61) RORARORCRORBPGRNR1H2
SCHEMBL14141741 0.83 RORA (1.00) RORARORCRORBPGRNR1H2
SCHEMBL13921919 0.82 RORA (0.57) RORARORCRORBPGRNPC1
SCHEMBL28813401 0.81 PGR (0.51) RORARORCRORBPGRALDH1A1
SCHEMBL16542086 0.78 RORA (0.55) RORARORCRORBPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080020323-A1 Light sensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2008-01-24 US disclosed
US-20080020323-A1 Light sensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2008-01-24 US disclosed