SCHEMBL28320105

SCHEMBL28320105

CCCCn1c2ccc(N)cc2c2cc(C(C)(C)C)ccc21

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RORA P35398 11/20 0.61
RORC P51449 11/20 0.61
RORB Q92753 11/20 0.61
PGR P06401 10/20 0.61
KDM4E B2RXH2 1/20 0.48
MEN1 O00255 1/20 0.48
ALDH1A1 P00352 1/20 0.48
MAPT P10636 1/20 0.48
HPGD P15428 1/20 0.48
MAPK1 P28482 1/20 0.48
HTT P42858 1/20 0.48
HBB P68871 1/20 0.48
KMT2A Q03164 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
HTR1D P28221 1/20 0.46
SIGMAR1 Q99720 1/20 0.43
NR1H2 P55055 1/20 0.42
NPC1 O15118 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29780772 1.00 RORA (0.61) RORARORCRORBPGRKDM4E
SCHEMBL29411056 0.89 ALDH1A1 (0.57) RORARORCRORBPGRKDM4E
SCHEMBL19974241 0.89 ALDH1A1 (0.57) RORARORCRORBPGRKDM4E
SCHEMBL22042197 0.84 RORA (0.63) RORARORCRORBPGRHTR1D
SCHEMBL22087154 0.84 RORA (0.63) RORARORCRORBPGRHTR1D
SCHEMBL14280407 0.84 RORA (0.71) RORARORCRORBPGRALDH1A1
SCHEMBL29208327 0.83 KDM4E (0.54) RORARORCRORBKDM4EMEN1
SCHEMBL30884614 0.83 KDM4E (0.54) RORARORCRORBKDM4EMEN1
SCHEMBL10945941 0.82 ALDH1A1 (0.71) RORARORCRORBPGRKDM4E
SCHEMBL31739343 0.82 ALDH1A1 (0.71) RORARORCRORBPGRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110167911-A Hole transport organic molecules for the group containing enamine of photoelectron and photoelectrochemicalcell cell 考纳斯科技大学 2019-08-23 CN disclosed