Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280599 | 0.94 | KDM4E (0.34) | KDM4ERECQLMAPK1MAOADYRK1A | |
| SCHEMBL14280617 | 0.90 | MAPK1 (0.41) | KDM4ETDP1MAPK1APPALDH1A1 | |
| SCHEMBL14280620 | 0.84 | KDM4E (0.31) | KDM4ETDP1MAPK1 | |
| SCHEMBL14280616 | 0.81 | KDM4E (0.50) | KDM4ERECQLTDP1MAPK1APP | |
| SCHEMBL15087926 | 0.79 | ALDH1A1 (0.42) | KDM4ETDP1MAPK1ALDH1A1LMNA | |
| SCHEMBL12299798 | 0.76 | ALDH1A1 (0.48) | KDM4ERECQLTDP1MAPK1APP | |
| SCHEMBL18070672 | 0.75 | KDM4E (0.37) | KDM4ERECQLTDP1MAPK1APP | |
| SCHEMBL14280603 | 0.75 | ACACB (0.42) | KDM4ERECQLAPP | |
| SCHEMBL13021583 | 0.75 | MEN1 (0.45) | KDM4ERECQLTDP1MAPK1MAOA | |
| SCHEMBL13413138 | 0.75 | KDM4E (0.42) | KDM4ERECQLTDP1MAPK1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021185-A1 | initiator systems; block polymers of vinyl acetate, vinyl alcohol, or polyvinyl butyral; use as water-soluble films, biodegradable and water-soluble polymers, detergents, in adhesives and as emulsifier; e.g. star polyethylene glycol modified with polyvinyl alcohol groups through a phenylene spacer | CELANESE VENTURES GMBH (DE) | 2008-01-24 | — | — | US | disclosed |
| US-20080021185-A1 | initiator systems; block polymers of vinyl acetate, vinyl alcohol, or polyvinyl butyral; use as water-soluble films, biodegradable and water-soluble polymers, detergents, in adhesives and as emulsifier; e.g. star polyethylene glycol modified with polyvinyl alcohol groups through a phenylene spacer | CELANESE VENTURES GMBH (DE) | 2008-01-24 | — | — | US | disclosed |