Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280620 | 0.93 | KDM4E (0.31) | MAPK1KDM4ETDP1MAPT | |
| SCHEMBL14280600 | 0.90 | KDM4E (0.39) | MAPK1KDM4ETDP1LMNAAPP | |
| SCHEMBL14280599 | 0.83 | KDM4E (0.34) | MAPK1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL14280618 | 0.77 | APP (0.47) | MAPK1KDM4ETDP1SMN1; SMN2NPC1 | |
| SCHEMBL14280628 | 0.74 | KDM4E (0.31) | MAPK1KDM4ETDP1 | |
| SCHEMBL15087926 | 0.71 | ALDH1A1 (0.42) | MAPK1KDM4ETDP1SMN1; SMN2MAPT | |
| SCHEMBL5442950 | 0.71 | ALDH1A1 (0.30) | ALDH1A1CASP1 | |
| SCHEMBL1742085 | 0.70 | APP (0.36) | MAPK1KDM4ETDP1SMN1; SMN2NCF1 | |
| SCHEMBL14280616 | 0.70 | KDM4E (0.50) | MAPK1KDM4ETDP1SMN1; SMN2MAPT | |
| SCHEMBL1742590 | 0.70 | APP (0.36) | MAPK1KDM4ETDP1SMN1; SMN2NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021185-A1 | initiator systems; block polymers of vinyl acetate, vinyl alcohol, or polyvinyl butyral; use as water-soluble films, biodegradable and water-soluble polymers, detergents, in adhesives and as emulsifier; e.g. star polyethylene glycol modified with polyvinyl alcohol groups through a phenylene spacer | CELANESE VENTURES GMBH (DE) | 2008-01-24 | — | — | US | disclosed |
| US-20080021185-A1 | initiator systems; block polymers of vinyl acetate, vinyl alcohol, or polyvinyl butyral; use as water-soluble films, biodegradable and water-soluble polymers, detergents, in adhesives and as emulsifier; e.g. star polyethylene glycol modified with polyvinyl alcohol groups through a phenylene spacer | CELANESE VENTURES GMBH (DE) | 2008-01-24 | — | — | US | disclosed |