SCHEMBL14280620

SCHEMBL14280620

ICc1cc(CI)cc(OCCOc2cc(CI)cc(CI)c2)c1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14280617 0.93 MAPK1 (0.41) KDM4EMAPK1TDP1MAPT
SCHEMBL15087926 0.77 ALDH1A1 (0.42) KDM4EMAPK1TDP1MAPT
SCHEMBL5442950 0.76 ALDH1A1 (0.30)
SCHEMBL14168915 0.74 APP (0.44)
SCHEMBL14280635 0.70 PRSS1 (0.30)
SCHEMBL14075734 0.69 HRH3 (0.50) KDM4EMAPT
SCHEMBL15763034 0.66 APP (0.57) MAPT
SCHEMBL14280603 0.66 ACACB (0.42) KDM4EMAPT
SCHEMBL14280628 0.66 KDM4E (0.31) KDM4EMAPK1TDP1
SCHEMBL16281533 0.65 ALDH1A1 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080021185-A1 initiator systems; block polymers of vinyl acetate, vinyl alcohol, or polyvinyl butyral; use as water-soluble films, biodegradable and water-soluble polymers, detergents, in adhesives and as emulsifier; e.g. star polyethylene glycol modified with polyvinyl alcohol groups through a phenylene spacer CELANESE VENTURES GMBH (DE) 2008-01-24 US disclosed