SCHEMBL14280635

SCHEMBL14280635

ICc1cc(OCCOc2cc(CI)c(CI)c(CI)c2)cc(CI)c1CI

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14280620 0.70 KDM4E (0.31)
SCHEMBL5487470 0.66
SCHEMBL14280617 0.65 MAPK1 (0.41)
SCHEMBL14168915 0.60 APP (0.44) PRSS1
SCHEMBL5929477 0.58 TP53 (0.52)
SCHEMBL14280628 0.58 KDM4E (0.31)
SCHEMBL9770391 0.57 KCNA3 (0.70)
SCHEMBL25868374 0.56 L3MBTL1 (0.35)
SCHEMBL17911619 0.55 MAPT (0.42)
SCHEMBL891206 0.55 HDAC3 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080021185-A1 initiator systems; block polymers of vinyl acetate, vinyl alcohol, or polyvinyl butyral; use as water-soluble films, biodegradable and water-soluble polymers, detergents, in adhesives and as emulsifier; e.g. star polyethylene glycol modified with polyvinyl alcohol groups through a phenylene spacer CELANESE VENTURES GMBH (DE) 2008-01-24 US disclosed
US-20080021185-A1 initiator systems; block polymers of vinyl acetate, vinyl alcohol, or polyvinyl butyral; use as water-soluble films, biodegradable and water-soluble polymers, detergents, in adhesives and as emulsifier; e.g. star polyethylene glycol modified with polyvinyl alcohol groups through a phenylene spacer CELANESE VENTURES GMBH (DE) 2008-01-24 US disclosed