SCHEMBL14280736

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	R-Fenoprofen SCHEMBL4082	0.82	PTGS1 (1.00)	PTGS1MEN1CYP2D6KMT2AAKR1C3
	Fenoprofen SCHEMBL8754928	0.82	PTGS1 (1.00)	PTGS1MEN1CYP2D6KMT2AAKR1C3
	R-Fenoprofen SCHEMBL30910976	0.82	PTGS1 (1.00)	PTGS1MEN1CYP2D6KMT2AAKR1C3
	Fenoprofen SCHEMBL11336376	0.82	PTGS1 (1.00)	PTGS1MEN1CYP2D6KMT2AAKR1C3
	Fenoprofen SCHEMBL3797	0.82	PTGS1 (1.00)	PTGS1MEN1CYP2D6KMT2AAKR1C3
	Fenoprofen SCHEMBL29481372	0.82	PTGS1 (1.00)	PTGS1MEN1CYP2D6KMT2AAKR1C3
	(S)-Fenoprofen SCHEMBL4492279	0.82	PTGS1 (1.00)	PTGS1MEN1CYP2D6KMT2AAKR1C3
	Fenoprofen SCHEMBL4081	0.81	PTGS1 (0.97)	PTGS1MEN1CYP2D6KMT2AAKR1C3
	Fenoprofen SCHEMBL11125651	0.81	PTGS1 (0.97)	PTGS1MEN1CYP2D6KMT2AAKR1C3
	Fenoprofen SCHEMBL8706502	0.81	PTGS1 (0.97)	PTGS1MEN1CYP2D6KMT2AAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.