SCHEMBL14280784

SCHEMBL14280784

C/C(=N\c1c2ccccc2cc2ccccc12)c1cccc(/C(C)=N/c2c3ccccc3cc3ccccc23)n1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.38
ERBB2 P04626 1/20 0.38
FYN P06241 1/20 0.38
MAOA P21397 1/20 0.38
ACHE P22303 1/20 0.38
AHR P35869 1/20 0.38
KMT2A Q03164 3/20 0.37
POLB P06746 2/20 0.37
AGTR1 P30556 1/20 0.37
CASP3 P42574 1/20 0.37
GFER P55789 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
ALDH1A1 P00352 3/20 0.36
HPGD P15428 3/20 0.36
HSD17B10 Q99714 2/20 0.36
PAX8 Q06710 1/20 0.35
KDM4E B2RXH2 3/20 0.35
CYP2C19 P33261 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14280791 0.90 CYP1A2 (0.44) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL7053595 0.82 TSHR (0.42) CYP1A2FYNACHEAHRKMT2A
SCHEMBL7053596 0.82 TSHR (0.42) CYP1A2FYNACHEAHRKMT2A
SCHEMBL6054984 0.80 MAPT (0.56) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL7053627 0.80 SIGMAR1 (0.48) KMT2APOLBAGTR1ALDH1A1KDM4E
SCHEMBL8091308 0.80 MAPT (0.56) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL7053624 0.80 SIGMAR1 (0.48) KMT2APOLBAGTR1ALDH1A1KDM4E
SCHEMBL5354574 0.77 SIGMAR1 (0.46) CYP1A2MAOAKMT2APOLBAGTR1
SCHEMBL5358995 0.77 SIGMAR1 (0.46) CYP1A2MAOAKMT2APOLBAGTR1
SCHEMBL14280783 0.75 SIGMAR1 (0.42) CYP1A2KMT2APAX8CYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080021180-A1 CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION REPSOL QUIMICA, S.A. 2008-01-24 US disclosed
US-20080021180-A1 CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION REPSOL QUIMICA, S.A. 2008-01-24 US disclosed