Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23982843 | 0.91 | NPC1 (0.36) | GABRA1GABRB2KCNK3KCNK9CYP1A2 | |
| SCHEMBL14280809 | 0.88 | ALDH1A1 (0.38) | KCNK3KCNK9CYP1A2NPSR1MAPT | |
| SCHEMBL14280801 | 0.86 | SIGMAR1 (0.42) | GABRA1GABRB2CYP1A2NPSR1MAPT | |
| SCHEMBL5587276 | 0.86 | SIGMAR1 (0.42) | GABRA1GABRB2CYP1A2NPSR1MAPT | |
| SCHEMBL23982591 | 0.86 | ALDH1A1 (0.35) | CYP1A2NPSR1MAPTMEN1HPGD | |
| SCHEMBL5589832 | 0.85 | SIGMAR1 (0.41) | GABRA1GABRB2KCNK3KCNK9CYP1A2 | |
| SCHEMBL23563259 | 0.83 | MEN1 (0.36) | CYP1A2NPSR1MAPTLMNAHTT | |
| SCHEMBL15307707 | 0.81 | KDR (0.41) | NPSR1MAPTLMNAHTTMEN1 | |
| SCHEMBL23982841 | 0.79 | MEN1 (0.38) | CYP1A2MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16077925 | 0.79 | ALDH1A1 (0.38) | CYP1A2NPSR1MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021180-A1 | CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION | REPSOL QUIMICA, S.A. | 2008-01-24 | — | — | US | disclosed |
| US-20080021180-A1 | CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION | REPSOL QUIMICA, S.A. | 2008-01-24 | — | — | US | disclosed |