Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23563259 | 0.91 | MEN1 (0.36) | ALDH1A1CYP1A2MAPTKMT2AMEN1 | |
| SCHEMBL14280804 | 0.88 | GABRA1 (0.39) | ALDH1A1CYP1A2MAPTKMT2AMEN1 | |
| SCHEMBL23982841 | 0.87 | MEN1 (0.38) | ALDH1A1CYP1A2MAPTKMT2AMEN1 | |
| SCHEMBL14280811 | 0.82 | ALDH1A1 (0.39) | ALDH1A1CYP1A2MAPTKMT2AMEN1 | |
| SCHEMBL5589752 | 0.82 | ALDH1A1 (0.39) | ALDH1A1CYP1A2MAPTKMT2AMEN1 | |
| SCHEMBL5587276 | 0.81 | SIGMAR1 (0.42) | ALDH1A1CYP1A2MAPTKMT2AMEN1 | |
| SCHEMBL14280801 | 0.81 | SIGMAR1 (0.42) | ALDH1A1CYP1A2MAPTKMT2AMEN1 | |
| SCHEMBL5589661 | 0.81 | ALDH1A1 (0.38) | ALDH1A1CYP1A2MAPTKMT2AMEN1 | |
| SCHEMBL23982843 | 0.81 | NPC1 (0.36) | ALDH1A1CYP1A2MAPTKMT2AMEN1 | |
| SCHEMBL5589832 | 0.80 | SIGMAR1 (0.41) | ALDH1A1CYP1A2MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021180-A1 | CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION | REPSOL QUIMICA, S.A. | 2008-01-24 | — | — | US | disclosed |