SCHEMBL14280808

SCHEMBL14280808

CC(C)c1ccccc1/N=C(\c1ccccc1)c1cccc(/C(=N/c2ccccc2C(C)C)c2ccccc2)n1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 7/20 0.43
NOS3 P29474 2/20 0.42
NOS1 P29475 2/20 0.42
NOS2 P35228 2/20 0.42
GRIN2D O15399 1/20 0.42
GRIN3B O60391 1/20 0.42
GRIN1 Q05586 1/20 0.42
GRIN2A Q12879 1/20 0.42
GRIN2B Q13224 1/20 0.42
GRIN2C Q14957 1/20 0.42
GRIN3A Q8TCU5 1/20 0.42
SCN5A Q14524 1/20 0.39
SCN2A Q99250 1/20 0.39
LMNA P02545 2/20 0.39
KMT2A Q03164 1/20 0.39
GABRA1 P14867 3/20 0.36
GABRB1 P18505 2/20 0.36
GAA P10253 1/20 0.36
GABRB2 P47870 2/20 0.35
FAAH O00519 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5589687 1.00 SIGMAR1 (0.43) SIGMAR1NOS3NOS1NOS2GRIN2D
SCHEMBL5588541 0.98 SIGMAR1 (0.42) SIGMAR1NOS3NOS1NOS2GRIN2D
SCHEMBL5589329 0.86 LMNA (0.43) SIGMAR1SCN5ASCN2ALMNAKMT2A
SCHEMBL16077914 0.86 LMNA (0.43) SIGMAR1SCN5ASCN2ALMNAKMT2A
SCHEMBL5589132 0.85 LMNA (0.42) SIGMAR1SCN5ASCN2ALMNAKMT2A
SCHEMBL5589912 0.85 ALDH1A1 (0.36) SCN5ASCN2ALMNAKMT2AGABRA1
SCHEMBL5587745 0.84 ALDH1A1 (0.36) SCN5ASCN2ALMNAKMT2AGABRA1
SCHEMBL5588460 0.81 LMNA (0.39) SCN5ASCN2ALMNAKMT2AGABRA1
SCHEMBL5589692 0.80 LMNA (0.38) SCN5ASCN2ALMNAKMT2AGABRA1
SCHEMBL4618229 0.80 SIGMAR1 (0.46) SIGMAR1NOS3NOS1NOS2GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9695260-B2 Method for producing olefin block polymer using plurality of types of transition metal catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-04 US disclosed
US-9695260-B2 Method for producing olefin block polymer using plurality of types of transition metal catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-04 US disclosed
US-20140275429-A1 METHOD FOR PRODUCING OLEFIN BLOCK POLYMER USING PLURALITY OF TYPES OF TRANSITION METAL CATALYSTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-09-18 US disclosed
US-20080021180-A1 CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION REPSOL QUIMICA, S.A. 2008-01-24 US disclosed