Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30587844 | 1.00 | CYP1A2 (0.53) | CYP1A2AKR1C3HDAC3ADAM17HDAC1 | |
| SCHEMBL5382427 | 0.84 | TP53 (0.55) | CYP1A2AKR1C3HDAC3ADAM17HDAC1 | |
| SCHEMBL8392279 | 0.82 | CYP1A2 (0.52) | CYP1A2AKR1C3HDAC3ADAM17HDAC1 | |
| SCHEMBL7069326 | 0.82 | CYP1A2 (0.52) | CYP1A2AKR1C3HDAC3ADAM17HDAC1 | |
| SCHEMBL7071411 | 0.82 | CYP1A2 (0.52) | CYP1A2AKR1C3HDAC3ADAM17HDAC1 | |
| SCHEMBL6933101 | 0.81 | AKR1C3 (0.60) | CYP1A2AKR1C3HDAC3ADAM17HDAC1 | |
| SCHEMBL6933104 | 0.81 | AKR1C3 (0.60) | CYP1A2AKR1C3HDAC3ADAM17HDAC1 | |
| SCHEMBL30587843 | 0.80 | HDAC3 (0.46) | CYP1A2AKR1C3HDAC3ADAM17HDAC1 | |
| SCHEMBL6669640 | 0.80 | CYP1A2 (0.53) | CYP1A2HDAC1SRD5A2 | |
| SCHEMBL6669641 | 0.80 | CYP1A2 (0.53) | CYP1A2HDAC1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250326718-A1 | 4-PHENYL-2-PYRROLIDINONES AND METHODS OF USING THEREOF | UNIV NORTH CAROLINA STATE (US) | 2025-10-23 | — | — | US | disclosed |
| EP-4504173-A2 | 4-PHENYL-2-PYRROLIDINONES AND METHODS OF USING THEREOF | North Carolina State University (US) | 2025-02-12 | — | — | EP | disclosed |
| WO-2023196678-A2 | 4-PHENYL-2-PYRROLIDINONES AND METHODS OF USING THEREOF | NORTH CAROLINA STATE UNIVERSITY (US) | 2023-10-12 | — | — | WO | disclosed |
| US-7317012-B2 | Bicyclic heterocycles as cannabinoind-1 receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-01-08 | — | — | US | disclosed |
| US-7317012-B2 | Bicyclic heterocycles as cannabinoind-1 receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250326718-A1 | 4-PHENYL-2-PYRROLIDINONES AND METHODS OF USING THEREOF | PGLS, ALG8, PFAS | CYP1A2 2205/4885AKR1C3 4764/4885HDAC3 294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.