Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8351920 | 0.85 | GAA (0.48) | PKMALDH1A1RAB9ALMNAMEN1 | |
| SCHEMBL22808741 | 0.77 | GAA (0.42) | PKMALDH1A1RAB9ALMNAMEN1 | |
| SCHEMBL24137901 | 0.74 | LMNA (0.51) | PKMALDH1A1RAB9ALMNAMEN1 | |
| SCHEMBL7175504 | 0.74 | PKM (0.54) | PKMALDH1A1RAB9ALMNAMEN1 | |
| Hydrochloric Acid SCHEMBL3069393 | 0.73 | ABAT (0.53) | PKMALDH1A1RAB9ALMNAMEN1 | |
| Benzene SCHEMBL27714747 | 0.73 | ABAT (0.53) | PKMALDH1A1RAB9ALMNAMEN1 | |
| SCHEMBL1330698 | 0.73 | ABAT (0.53) | PKMALDH1A1RAB9ALMNAMEN1 | |
| SCHEMBL41828 | 0.73 | ABAT (0.53) | PKMALDH1A1RAB9ALMNAMEN1 | |
| SCHEMBL7785939 | 0.73 | ABAT (0.53) | PKMALDH1A1RAB9ALMNAMEN1 | |
| Hydrochloric Acid SCHEMBL2006870 | 0.73 | ABAT (0.53) | PKMALDH1A1RAB9ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021079-A1 | Compounds, Compositions, and Methods | CYTOKINETICS, INC. | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021079-A1 | Compounds, Compositions, and Methods | ALPP, PCNA, MKI67 | PKM 572/4885ALDH1A1 2465/4885RAB9A 2411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.