SCHEMBL14281166

SCHEMBL14281166

O=S1(=O)c2ccccc2N(CCCN2c3ccccc3S(=O)(=O)c3ccccc32)c2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 2/20 0.61
TP53 P04637 3/20 0.56
LMNA P02545 6/20 0.54
MAPT P10636 4/20 0.54
THRB P10828 1/20 0.54
POLB P06746 1/20 0.54
HDAC1 Q13547 2/20 0.49
HDAC6 Q9UBN7 2/20 0.49
HDAC3 O15379 1/20 0.49
TUBB4A P04350 1/20 0.49
TUBB P07437 1/20 0.49
TUBA3C P0DPH7 1/20 0.49
HDAC4 P56524 1/20 0.49
TUBA1B P68363 1/20 0.49
TUBA4A P68366 1/20 0.49
TUBB4B P68371 1/20 0.49
TUBB3 Q13509 1/20 0.49
TUBB2A Q13885 1/20 0.49
TUBB8 Q3ZCM7 1/20 0.49
TUBA3E Q6PEY2 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10349326 0.86 CES1 (0.53) RXFP1TP53LMNAMAPTTHRB
SCHEMBL4194693 0.86 CES1 (0.53) RXFP1TP53LMNAMAPTTHRB
SCHEMBL11182750 0.86 RXFP1 (0.51) RXFP1TP53LMNAMAPTTHRB
SCHEMBL32667803 0.86 CES1 (0.53) RXFP1TP53LMNAMAPTTHRB
SCHEMBL1302641 0.84 LMNA (0.58) RXFP1TP53LMNAMAPTTHRB
SCHEMBL14281167 0.83 RXFP1 (0.66) RXFP1TP53LMNAMAPTTHRB
SCHEMBL12349341 0.82 RXFP1 (0.56) RXFP1TP53LMNAMAPTTHRB
SCHEMBL12349334 0.80 RXFP1 (0.53) RXFP1TP53LMNAMAPTTHRB
SCHEMBL4307189 0.79 RXFP1 (0.61) RXFP1TP53LMNAMAPTTHRB
SCHEMBL30433630 0.79 RXFP1 (0.61) RXFP1TP53LMNAMAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080018238-A1 Use Of Phenothiazine-S-Oxides And Phenothiazine -S,S-Dioxides In The Form Of Matrix Materials For Organic Light-Emitting Diodes BASF AKTIENGESELLSCHAFT (DE) 2008-01-24 US disclosed
US-20080018238-A1 Use Of Phenothiazine-S-Oxides And Phenothiazine -S,S-Dioxides In The Form Of Matrix Materials For Organic Light-Emitting Diodes BASF AKTIENGESELLSCHAFT (DE) 2008-01-24 US disclosed