Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 9/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | HTR1A | P08908 | 7/20 | 0.58 |
| ▸ | DRD2 | P14416 | 7/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.58 |
| ▸ | HRH1 | P35367 | 6/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.58 |
| ▸ | TP53 | P04637 | 6/20 | 0.58 |
| ▸ | HTR2A | P28223 | 5/20 | 0.58 |
| ▸ | HTR6 | P50406 | 5/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.58 |
| ▸ | DRD1 | P21728 | 5/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.58 |
| ▸ | DRD3 | P35462 | 5/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.58 |
| ▸ | SLC22A1 | O15245 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5153952 | 0.88 | MAPT (0.59) | LMNACYP2D6MAPTHTR1ADRD2 | |
| SCHEMBL9768806 | 0.85 | CYP2D6 (0.56) | LMNACYP2D6MAPTHTR1ADRD2 | |
| SCHEMBL14281166 | 0.84 | RXFP1 (0.61) | LMNAMAPTHTR1ATP53HTR2A | |
| SCHEMBL10349326 | 0.79 | CES1 (0.53) | LMNAMAPTTP53ALDH1A1CNR1 | |
| SCHEMBL4194693 | 0.79 | CES1 (0.53) | LMNAMAPTTP53ALDH1A1CNR1 | |
| SCHEMBL32667803 | 0.79 | CES1 (0.53) | LMNAMAPTTP53ALDH1A1CNR1 | |
| SCHEMBL11182750 | 0.75 | RXFP1 (0.51) | LMNAMAPTHTR1ATP53HTR2A | |
| Depramine SCHEMBL29489714 | 0.75 | HTR1A (0.73) | LMNACYP2D6MAPTHTR1ADRD2 | |
| SCHEMBL12265301 | 0.75 | CYP2D6 (0.66) | LMNACYP2D6MAPTHTR1ADRD2 | |
| Depramine SCHEMBL2108027 | 0.75 | HTR1A (0.73) | LMNACYP2D6MAPTHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226084-A9 | HIGH PENETRATION PRODRUG COMPOSITIONS AND PHARMACEUTICAL COMPOSITION THEREOF FOR TREATMENT OF PULMONARY CONDITIONS | TECHFIELDS PHARMA CO., LTD. (CN) | 2024-07-11 | — | — | US | claimed |
| US-20240131017-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS AND PHARMACEUTICAL COMPOSITION THEREOF FOR TREATMENT OF PULMONARY CONDITIONS | TECHFIELDS PHARMA CO., LTD. (CN) | 2024-04-25 | — | — | US | claimed |
| US-20240115562-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS AND PHARMACEUTICAL COMPOSITION THEREOF FOR TREATMENT OF PULMONARY CONDITIONS | TECHFIELDS PHARMA CO., LTD. (CN) | 2024-04-11 | — | — | US | claimed |
| CN-115703749-A | Dioxopropizine hydrochloride nitrogen oxide and preparation method thereof | 河南优凯制药有限公司 | 2023-02-17 | — | — | CN | claimed |
| CN-111943910-B | Dioxopropazine hydrochloride and preparation method thereof | 上海金不换兰考制药有限公司 | 2022-09-09 | — | — | CN | claimed |
| CN-114609310-A | Sample pretreatment method and detection method for detecting sedative residue in milk by chromatography-mass spectrometry | 中国农业科学院农业质量标准与检测技术研究所 | 2022-06-10 | — | — | CN | claimed |
| CN-111943910-A | Dioxopropazine hydrochloride and preparation method thereof | 河南优凯制药有限公司 | 2020-11-17 | — | — | CN | claimed |
| CN-111419960-A | Compound antitussive pharmaceutical composition and preparation method thereof | 辽宁修和药业有限公司 | 2020-07-17 | — | — | CN | claimed |
| CN-109833403-A | A kind of formula of cold drug | 徐彩玲 | 2019-06-04 | — | — | CN | claimed |
| CN-106732475-B | A kind of HPLC chiral stationary phase and its preparation method and application | 青岛大学 | 2019-05-28 | — | — | CN | claimed |
| CN-1478477-A | Pectoral | 王鹏程 | 2004-03-03 | — | — | CN | claimed |
| CN-1094060-C | Medicinal composition for treating cough and preparation process thereof | WANG SHOUDONG (CN) | 2002-11-13 | — | — | CN | claimed |
| CN-1379047-A | Match of organic medicine and beta-cyclodextrin derivative and its preparing process | LIU YUNQING (CN) | 2002-11-13 | — | — | CN | claimed |
| CN-1358534-A | Compound medicine for treating bronchial asthma and preparation process | WANG ZHIQIANG (CN) | 2002-07-17 | — | — | CN | claimed |
| CN-1058176-C | Compounded Chuanlin Dingchuan capsule for asthma | LIU GUANGQING (CN) | 2000-11-08 | — | — | CN | claimed |
| CN-1267537-A | Medicinal composition for asthma and trachitis and its preparation | WANG XINSHAN (CN) | 2000-09-27 | — | — | CN | claimed |
| CN-1256942-A | Medicinal composition for treating cough and preparation process thereof | WANG SHOUDONG (CN) | 2000-06-21 | — | — | CN | claimed |
| CN-1239670-A | Compound capsule for treating asthma | TIAN KAIGUI (CN) | 1999-12-29 | — | — | CN | claimed |
| CN-1232671-A | Compound kechuankang capsule for cough and asthma | LIU ZEHUA (CN) | 1999-10-27 | — | — | CN | claimed |
| CN-1179976-A | Huatan Pingchuanjing medicine for curing respiratory system diseases | YIN QINGCHENG (CN) | 1998-04-29 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240226084-A9 | HIGH PENETRATION PRODRUG COMPOSITIONS AND PHARMACEUTICAL COMPOSITION THEREOF FOR TREATMENT OF PULMONARY CONDITIONS | HRH4, HCAR2, PAH | LMNA 1999/4885CYP2D6 153/4885MAPT 2541/4885 |
| US-20240115562-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS AND PHARMACEUTICAL COMPOSITION THEREOF FOR TREATMENT OF PULMONARY CONDITIONS | HRH4, HCAR2, PAH | LMNA 1999/4885CYP2D6 153/4885MAPT 2541/4885 |
| US-20240131017-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS AND PHARMACEUTICAL COMPOSITION THEREOF FOR TREATMENT OF PULMONARY CONDITIONS | HRH4, HCAR2, PAH | LMNA 1999/4885CYP2D6 153/4885MAPT 2541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.