Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | LPL | P06858 | 1/20 | 0.56 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.56 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.56 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.56 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.56 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5586183 | 0.82 | ORAI1 (0.67) | CA2LPLLIPGORAI1ORAI2 | |
| SCHEMBL1290227 | 0.80 | ENPP2 (0.52) | CA2ACHECA1ENPP2ALDH1A1 | |
| SCHEMBL27965000 | 0.78 | CA2 (0.54) | CA2LPLLIPGORAI1ORAI2 | |
| SCHEMBL25825730 | 0.78 | CA2 (0.38) | CA2LPLLIPGORAI1ORAI2 | |
| SCHEMBL2320469 | 0.78 | CA2 (0.54) | CA2LPLLIPGORAI1ORAI2 | |
| SCHEMBL16247935 | 0.78 | ORAI1 (0.54) | CA2LPLLIPGORAI1ORAI2 | |
| SCHEMBL3918805 | 0.78 | CA2 (0.54) | CA2LPLLIPGORAI1ORAI2 | |
| SCHEMBL5926479 | 0.78 | TDP1 (0.42) | CA2ACHETDP1CA1ENPP2 | |
| SCHEMBL13686655 | 0.78 | CA1 (0.67) | CA2ACHETDP1CA1ENPP2 | |
| SCHEMBL14068806 | 0.78 | ENPP2 (0.54) | CA2LPLLIPGORAI1ORAI2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131333-A1 | BENZIMIDAZOLE COMPOUND AND MEDICAL USE THEREOF | 中国科学院上海药物研究所 | 2023-07-13 | — | — | WO | disclosed |
| US-20080009431-A1 | Enzyme stabilization | PROCTER & GAMBLE COMPANY, THE | 2008-01-10 | — | — | US | disclosed |
| US-20080009431-A1 | Enzyme stabilization | PROCTER & GAMBLE COMPANY, THE | 2008-01-10 | — | — | US | disclosed |