SCHEMBL5586183

SCHEMBL5586183

Cc1ccc(B(O)OB(O)c2ccc(C)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ORAI1 Q96D31 2/20 0.67
ORAI2 Q96SN7 2/20 0.67
ORAI3 Q9BRQ5 2/20 0.67
TRPV6 Q9H1D0 2/20 0.67
CA2 P00918 3/20 0.59
LPL P06858 1/20 0.59
LIPG Q9Y5X9 1/20 0.59
ACHE P22303 5/20 0.42
TDP1 Q9NUW8 2/20 0.42
CA1 P00915 3/20 0.38
ENPP2 Q13822 1/20 0.36
ALDH1A1 P00352 3/20 0.35
LMNA P02545 2/20 0.35
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5600076 0.88 ORAI1 (0.58) ORAI1ORAI2ORAI3TRPV6CA2
SCHEMBL28299770 0.82 ORAI1 (0.47) ORAI1ORAI2ORAI3TRPV6CA2
SCHEMBL14282970 0.82 CA2 (0.56) ORAI1ORAI2ORAI3TRPV6CA2
SCHEMBL2964428 0.80 TRPV6 (1.00) ORAI1ORAI2ORAI3TRPV6CA2
SCHEMBL27965000 0.80 CA2 (0.54) ORAI1ORAI2ORAI3TRPV6CA2
SCHEMBL3918805 0.80 CA2 (0.54) ORAI1ORAI2ORAI3TRPV6CA2
SCHEMBL2320469 0.80 CA2 (0.54) ORAI1ORAI2ORAI3TRPV6CA2
SCHEMBL6974398 0.78 ORAI1 (0.47) ORAI1ORAI2ORAI3TRPV6CA2
SCHEMBL5953336 0.77 LPL (0.50) ORAI1ORAI2ORAI3TRPV6CA2
SCHEMBL16653533 0.75 CA1 (0.67) CA2ACHETDP1CA1ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3070126-B1 AROMATIC POLYCARBONATE RESIN MOLDING IDEMITSU KOSAN CO (JP) 2020-05-06 EP disclosed
EP-2949655-B1 REACTION CATALYST FOR CROSS COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND HOKKO CHEM IND CO (JP) 2019-05-15 EP disclosed
US-10221279-B2 Polycarbonate resin molding material IDEMITSU KOSAN CO., LTD. (JP) 2019-03-05 US disclosed
EP-3070125-B1 POLYCARBONATE RESIN MOLDING MATERIAL IDEMITSU KOSAN CO (JP) 2018-07-04 EP disclosed
US-9963580-B2 Rubber composition and pneumatic tire using same THE YOKOHAMA RUBBER CO., LTD. (JP) 2018-05-08 US disclosed
US-20170298176-A1 POLYCARBONATE RESIN MOLDING MATERIAL IDEMITSU KOSAN CO., LTD. (JP) 2017-10-19 US disclosed
US-9732185-B2 Polycarbonate resin molding material IDEMITSU KOSAN CO., LTD. (JP) 2017-08-15 US disclosed
US-9707551-B2 Reaction catalyst for cross-coupling and method for manufacturing aromatic compound HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 2017-07-18 US disclosed
US-9670316-B2 Aromatic polycarbonate resin molding IDEMITSU KOSAN CO., LTD. (JP) 2017-06-06 US disclosed
US-9480166-B2 Method of manufacturing non-firing type electrode E I DU PONT DE NEMOURS AND COMPANY (US) 2016-10-25 US disclosed
EP-2986666-A1 METHOD OF MANUFACTURING NON-FIRED TYPE ELECTRODE E. I. du Pont de Nemours and Company (US) 2016-02-24 EP disclosed
US-20150360214-A1 REACTION CATALYST FOR CROSS-COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 2015-12-17 US disclosed
EP-2949655-A1 REACTION CATALYST FOR CROSS COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND Hokko Chemical Industry Co., Ltd. (JP) 2015-12-02 EP disclosed
US-20150337117-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE USING SAME THE YOKOHAMA RUBBER CO., LTD. (JP) 2015-11-26 US disclosed
US-20150315324-A1 TERMINAL BORINIC ACID GROUP-MODIFIED POLYMER, METHOD OF MANUFACTURING THE SAME AND RUBBER COMPOSITION CONTAINING THE SAME THE YOKOHAMA RUBBER CO., LTD. (JP) 2015-11-05 US disclosed
US-9127145-B2 Rubber composition and pneumatic tire using same THE YOKOHAMA RUBBER CO., LTD. (JP) 2015-09-08 US disclosed
US-20150111985-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE USING SAME THE YOKOHAMA RUBBER CO., LTD. (JP) 2015-04-23 US disclosed
WO-2014172137-A1 METHOD OF MANUFACTURING NON-FIRED TYPE ELECTRODE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2014-10-23 WO disclosed
US-20140306165-A1 METHOD OF MANUFACTURING NON-FIRING TYPE ELECTRODE E I DU PONT DE NEMOURS AND COMPANY (US) 2014-10-16 US disclosed
US-7217477-B2 Organometallic compound which decomposes when overvoltage is applying LG CHEM, LTD. (KR) 2007-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150360214-A1 REACTION CATALYST FOR CROSS-COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND ALK, HRH4, HRH3 ORAI1 575/4885ORAI2 231/4885ORAI3 473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.