Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | VDR | P11473 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 4/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433807 | 0.87 | TERT (0.49) | NR1I2CYP1A2VDRCYP2C9CYP2B6 | |
| SCHEMBL30081962 | 0.87 | TERT (0.49) | NR1I2CYP1A2VDRCYP2C9CYP2B6 | |
| SCHEMBL14285065 | 0.83 | STAT3 (0.50) | TERTTOP1 | |
| SCHEMBL14285084 | 0.82 | TOP1 (0.39) | TERTMAPK13RAF1MAPK12MAPK11 | |
| SCHEMBL13907391 | 0.80 | STAT3 (0.50) | TERTABCG2TOP1 | |
| SCHEMBL17687648 | 0.80 | TERT (0.43) | NR1I2CYP1A2VDRCYP2C9CYP2B6 | |
| SCHEMBL14703823 | 0.78 | ADORA2A (0.43) | TERTMAPK13RAF1MAPK12MAPK11 | |
| SCHEMBL14703874 | 0.77 | TERT (0.41) | NR1I2CYP1A2VDRCYP2C9CYP2B6 | |
| SCHEMBL17687652 | 0.75 | STAT3 (0.57) | NR1I2CYP1A2VDRCYP2C9CYP2B6 | |
| SCHEMBL498495 | 0.74 | TERT (0.51) | TERTKDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7319147-B2 | Porphyrins and related compounds | BIOSCIENCE TECHNOLOGY INVESTMENT HOLDINGS LIMITED (MY) | 2008-01-15 | — | — | US | disclosed |
| US-7319147-B2 | Porphyrins and related compounds | BIOSCIENCE TECHNOLOGY INVESTMENT HOLDINGS LIMITED (MY) | 2008-01-15 | — | — | US | disclosed |