SCHEMBL498495

SCHEMBL498495

COc1cc(OC)cc(-c2c3nc(c(-c4cc(OC)cc(OC)c4)c4ccc([nH]4)c(-c4cc(OC)cc(OC)c4)c4nc(c(-c5cc(OC)cc(OC)c5)c5ccc2[nH]5)C=C4)C=C3)c1

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 6/20 0.51
▸ ABCG2 Q9UNQ0 1/20 0.48
▸ TOP1 P11387 4/20 0.46
▸ CYCS P99999 3/20 0.45
▸ ENPP2 Q13822 1/20 0.44
▸ KDM4E B2RXH2 1/20 0.42
▸ MEN1 O00255 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ MAPT P10636 1/20 0.42
▸ TSHR P16473 1/20 0.42
▸ GFER P55789 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29408468 1.00 TERT (0.51) TERTABCG2TOP1CYCSENPP2
SCHEMBL7261646 0.90 TOP1 (0.60) TERTABCG2TOP1CYCSENPP2
SCHEMBL5015256 0.88 TERT (0.42) TERTABCG2TOP1CYCSENPP2
SCHEMBL433807 0.86 TERT (0.49) TERTABCG2KDM4EMEN1MAPT
SCHEMBL30081962 0.86 TERT (0.49) TERTABCG2KDM4EMEN1MAPT
SCHEMBL949511 0.85 TERT (0.57) TERTABCG2TOP1CYCSENPP2
SCHEMBL29414382 0.85 TERT (0.57) TERTABCG2TOP1CYCSENPP2
SCHEMBL6804332 0.84 STAT3 (0.59) TERTABCG2TOP1KDM4EMEN1
SCHEMBL8430292 0.83 TERT (0.55) TERTABCG2TOP1CYCSENPP2
SCHEMBL22265228 0.83 TERT (0.55) TERTABCG2TOP1CYCSENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9867800-B2 Method of quenching singlet and triplet excited states of pigments, such as porphyrin compounds, particularly protoporphyrin IX, with conjugated fused tricyclic compounds have electron withdrawing groups, to reduce generation of reactive oxygen species, particularly singlet oxygen HALLSTAR INNOVATIONS CORP. (US) 2018-01-16 — — US claimed
CN-106711400-A Anode plate and secondary battery 宁德新能源科技有限公司 2017-05-24 — — CN claimed
US-20150164852-A1 METHOD OF QUENCHING SINGLET AND TRIPLET EXCITED STATES OF PIGMENTS, SUCH AS PORPHYRIN COMPOUNDS, PARTICULARLY PROTOPORPHYRIN IX, WITH CONJUGATED FUSED TRICYCLIC COMPOUNDS HAVE ELECTRON WITHDRAWING GROUPS, TO REDUCE GENERATION OF REACTIVE OXYGEN SPECIES, PARTICULARLY SINGLET OXYGEN HALLSTAR INNOVATIONS CORP. (US) 2015-06-18 — — US claimed
WO-2014025370-A1 TRICYCLIC ENERGY QUENCHER COMPOUNDS FOR REDUCING SINGLET OXYGEN GENERATION HALLSTAR INNOVATIONS CORP. (US) 2014-02-13 — — WO claimed
US-11935803-B2 Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer and semiconductor device MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-03-19 — — US disclosed
US-20230226544-A1 ION-SELECTIVE MEMBRANE, ION-SELECTIVE ELECTRODE, ION SENSOR, SPECIMEN TESTING DEVICE, AND COMPLEX COMPOUND CANON KABUSHIKI KAISHA (JP) 2023-07-20 — — US disclosed
US-20230226544-A1 ION-SELECTIVE MEMBRANE, ION-SELECTIVE ELECTRODE, ION SENSOR, SPECIMEN TESTING DEVICE, AND COMPLEX COMPOUND CANON KABUSHIKI KAISHA (JP) 2023-07-20 — — US disclosed
US-11697737-B2 Color material dispersion liquid, composition, film, optical filter and display device DAI NIPPON PRINTING CO., LTD. (JP) 2023-07-11 — — US disclosed
US-20230094496-A1 COLOR MATERIAL DISPERSION LIQUID, COMPOSITION, FILM, OPTICAL FILTER AND DISPLAY DEVICE DAI NIPPON PRINTING CO., LTD. (JP) 2023-03-30 — — US disclosed
US-11518888-B2 Color material dispersion liquid, composition, film, optical filter and display device DAI NIPPON PRINTING CO., LTD. (JP) 2022-12-06 — — US disclosed
EP-3077467-B1 DRIER COMPOSITION AND USE THEREOF PPG EUROPE B V (NL) 2022-11-02 — — EP disclosed
US-20220071956-A1 COMPOSITION FOR SUPRESSING SECRETION OF EXTRACELLULAR VESICLES NISSAN CHEMICAL CORPORATION (JP) 2022-03-10 — — US disclosed
US-20110070153-A1 Artificial cells SEARETE, LLC, A LIMITED LIABILITY CORPORATION OF THE STATE OF DELAWARE 2011-03-24 — — US disclosed
US-20100247447-A1 DRUG DELIVERY SYSTEM FOR HYDROPHOBIC DRUGS BAUSCH HEALTH COMPANIES INC. (CA) 2010-09-30 — — US disclosed
WO-2010095276-A1 METHOD FOR PREPARING ELECTRODE CATALYST FOR FUEL CELL AND SOLID POLYMER FUEL CELL TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2010-08-26 — — WO disclosed
US-20100041133-A1 Biological targeting compositions and methods of using the same SEARETE LLC, A LIMITED LIABILITY CORPORATION OF THE STATE OF DELAWARE 2010-02-18 — — US disclosed
US-20100042072-A1 Biological targeting compositions and methods of using the same SEARETE LLC, A LIMITED LIABILITY CORPORATION OF THE STATE OF DELAWARE 2010-02-18 — — US disclosed
US-20100041014-A1 Biological targeting compositions and methods of using the same ENTERPRISE SCIENCE FUND, LLC 2010-02-18 — — US disclosed
US-20070086973-A1 Drug delivery systems for photodynamic therapy THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2007-04-19 — — US disclosed
US-6609014-B1 Use of PDT to inhibit intimal hyperplasia QLT INC. (CA) 2003-08-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070086973-A1 Drug delivery systems for photodynamic therapy PIN1, PPOX, DHFR TERT 3224/4885ABCG2 368/4885TOP1 1303/4885
US-20100247447-A1 DRUG DELIVERY SYSTEM FOR HYDROPHOBIC DRUGS LIPA, MLEC, ABCG2 TERT 4251/4885ABCG2 3/4885TOP1 3220/4885
US-20230226544-A1 ION-SELECTIVE MEMBRANE, ION-SELECTIVE ELECTRODE, ION SENSOR, SPECIMEN TESTING DEVICE, AND COMPLEX COMPOUND LETM1, TIMM9, TMEM109 TERT 1608/4885ABCG2 478/4885TOP1 3904/4885
US-20150164852-A1 METHOD OF QUENCHING SINGLET AND TRIPLET EXCITED STATES OF PIGMENTS, SUCH AS PORPHYRIN COMPOUNDS, PARTICULARLY PROTOPORPHYRIN IX, WITH CONJUGATED FUSED TRICYCLIC COMPOUNDS HAVE ELECTRON WITHDRAWING GROUPS, TO REDUCE GENERATION OF REACTIVE OXYGEN SPECIES, PARTICULARLY SINGLET OXYGEN NOX3, CBR3, CCR3 TERT 1768/4885ABCG2 2540/4885TOP1 1886/4885
US-20220071956-A1 COMPOSITION FOR SUPRESSING SECRETION OF EXTRACELLULAR VESICLES EXOSC9, EXOSC10, EXOSC5 TERT 2836/4885ABCG2 3819/4885TOP1 4854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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