Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.39 |
| ▸ | TERT | O14746 | 3/20 | 0.39 |
| ▸ | CYCS | P99999 | 3/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14285065 | 0.86 | STAT3 (0.50) | TOP1TERTCYCSENPP2STAT3 | |
| SCHEMBL249199 | 0.85 | TOP1 (0.50) | TOP1TERTCYCSENPP2STAT3 | |
| SCHEMBL29556430 | 0.85 | TOP1 (0.50) | TOP1TERTCYCSENPP2STAT3 | |
| SCHEMBL31296593 | 0.85 | TOP1 (0.50) | TOP1TERTCYCSENPP2STAT3 | |
| SCHEMBL30297908 | 0.84 | TERT (0.51) | TOP1TERTCYCSENPP2STAT3 | |
| SCHEMBL29648445 | 0.84 | TERT (0.51) | TOP1TERTCYCSENPP2STAT3 | |
| SCHEMBL8865323 | 0.84 | TERT (0.51) | TOP1TERTCYCSENPP2STAT3 | |
| SCHEMBL13907391 | 0.83 | STAT3 (0.50) | TOP1TERTCYCSENPP2STAT3 | |
| SCHEMBL14285083 | 0.82 | NR1I2 (0.40) | TOP1TERTMAPK13RAF1MAPK12 | |
| SCHEMBL1640992 | 0.82 | TOP1 (0.54) | TOP1TERTCYCSENPP2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7319147-B2 | Porphyrins and related compounds | BIOSCIENCE TECHNOLOGY INVESTMENT HOLDINGS LIMITED (MY) | 2008-01-15 | — | — | US | disclosed |
| US-7319147-B2 | Porphyrins and related compounds | BIOSCIENCE TECHNOLOGY INVESTMENT HOLDINGS LIMITED (MY) | 2008-01-15 | — | — | US | disclosed |