Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14286351 | 0.89 | ALDH1A1 (0.48) | GAAALDH1A1KDM4EMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL29837525 | 0.88 | SMN1; SMN2 (0.49) | GAAALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL30130190 | 0.79 | TSHR (0.43) | GAAALDH1A1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL20932772 | 0.79 | TSHR (0.43) | GAAALDH1A1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL22275736 | 0.77 | CYP1A2 (0.50) | GAAKMT2ACYP1A2CYP2D6 | |
| SCHEMBL22263146 | 0.77 | SIGMAR1 (0.49) | GAA | |
| SCHEMBL20920797 | 0.76 | ALDH1A1 (0.44) | GAAALDH1A1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL20917799 | 0.75 | CYP1A2 (0.44) | GAAMAPTKMT2ASMN1; SMN2GFER | |
| SCHEMBL20932774 | 0.75 | CYP1A2 (0.48) | KMT2ACYP1A2CYP2D6 | |
| SCHEMBL20932675 | 0.74 | SIGMAR1 (0.41) | GAAKMT2AGFERKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008025152-A1 | ANTIBACTERIAL AGENTS | MCMASTER UNIVERSITY (CA) | 2008-03-06 | — | — | WO | disclosed |