Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20932772 | 1.00 | TSHR (0.43) | TSHRCYP1A2CYP2D6IDO1KMT2A | |
| SCHEMBL31396442 | 0.89 | KMT2A (0.53) | TSHRCYP1A2CYP2D6KMT2ALMNA | |
| SCHEMBL20920832 | 0.89 | KMT2A (0.53) | TSHRCYP1A2CYP2D6KMT2ALMNA | |
| SCHEMBL20932660 | 0.85 | KMT2A (0.45) | TSHRCYP1A2CYP2D6KMT2ALMNA | |
| SCHEMBL30130108 | 0.85 | KMT2A (0.45) | TSHRCYP1A2CYP2D6KMT2ALMNA | |
| SCHEMBL20920797 | 0.85 | ALDH1A1 (0.44) | TSHRCYP1A2CYP2D6KMT2ALMNA | |
| SCHEMBL20917818 | 0.83 | KMT2A (0.46) | TSHRCYP1A2CYP2D6KMT2ALMNA | |
| SCHEMBL22275641 | 0.82 | KMT2A (0.42) | TSHRCYP1A2CYP2D6KMT2ALMNA | |
| SCHEMBL20932774 | 0.82 | CYP1A2 (0.48) | TSHRCYP1A2CYP2D6KMT2ALMNA | |
| SCHEMBL22263103 | 0.81 | KMT2A (0.47) | TSHRCYP1A2CYP2D6KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220380305-A1 | IDO/TDO Inhibitor | CANBAS CO., LTD. | 2022-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220380305-A1 | IDO/TDO Inhibitor | IDO1, IDO2, TDO2 | TSHR 266/4885CYP1A2 508/4885CYP2D6 948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.