Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 16/20 | 0.57 |
| ▸ | RBBP9 | O75884 | 1/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6897257 | 0.78 | SIGMAR1 (0.54) | TBXAS1TBXA2RSIGMAR1 | |
| SCHEMBL6142534 | 0.76 | RBBP9 (0.46) | TBXAS1RBBP9PLA2G4ACES1 | |
| SCHEMBL6142531 | 0.76 | RBBP9 (0.46) | TBXAS1RBBP9PLA2G4ACES1 | |
| SCHEMBL14288482 | 0.75 | HDAC1 (0.50) | TBXAS1TBXA2RSIGMAR1 | |
| SCHEMBL8094515 | 0.73 | SIGMAR1 (0.53) | TBXAS1TBXA2RSIGMAR1 | |
| SCHEMBL9528067 | 0.72 | TBXAS1 (0.72) | TBXAS1TBXA2R | |
| SCHEMBL9528079 | 0.72 | TBXAS1 (0.72) | TBXAS1TBXA2R | |
| SCHEMBL9530856 | 0.72 | TBXAS1 (0.72) | TBXAS1TBXA2R | |
| SCHEMBL11229130 | 0.72 | TBXAS1 (0.54) | TBXAS1SIGMAR1 | |
| SCHEMBL11792681 | 0.72 | TBXAS1 (0.54) | TBXAS1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7320993-B1 | Aryl-substituted pyridylalkane, alkene, and alkine carboxamides useful as cytostatic useful as cytostatic and immuosuppressive agents | ASTELLAS DEUTSCHLAND GMBH (DE) | 2008-01-22 | — | — | US | disclosed |